AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) TERHADAP METHICILLIN-RESISTANT Staphylococcus aureus (MRSA)

Sulistiyowati, Dwi (2017) AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) TERHADAP METHICILLIN-RESISTANT Staphylococcus aureus (MRSA). Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Soursop leaf (Annona muricata L) is a plant that is empirically used to treat cancer. Some studies suggest that soursop leaves have antibacterial activity against Staphylococcus aureus, Bacillus subtilis, K. pneumonia, S. typhimurium, E. coli. Secondary metabolite compounds contained in soursop leaves include saponins, tannins and flavonoids. MRSA is a strain of S. aureus that has the mecA gene, where the gene encodes PBP2a that having a low affinity for beta-lactam antibiotics. This research was conducted to find out antibacterial activity of 70% ethanol extract soursop leaf againts MRSA. The extraction was done by maceration method using 70% ethanol solvent. Examination of antibacterial activity of MRSA by diffusion of disc and well at concentration 25%, 50%, 75% and dilution with concentration 75%, 37,5%, 18,75%, 9,37%, 4,69%, 2, 34%, 1.17%, 0.59%. The results of this study showed that 70% ethanol extract of soursop leaves 25%, 50%, 75% concentration did not inhibit and killing MRSA growth Keywords : Annona muricata L., MRSA, antibacterial, extract.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Annona muricata L., MRSA, antibacterial, extract
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Rohma Tri Wardani
Date Deposited:	25 Feb 2019 03:07
Last Modified:	25 Feb 2019 03:07
URI:	http://repo.setiabudi.ac.id/id/eprint/1005

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