UJI AKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN LEUNCA (Solanum nigrum L.) DENGAN METODE TAIL FLICK DAN WRITHING TEST

Dewi, Fitri Jaya Santi Utami (2017) UJI AKTIVITAS ANALGESIK EKSTRAK ETANOL DAUN LEUNCA (Solanum nigrum L.) DENGAN METODE TAIL FLICK DAN WRITHING TEST. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Analgesic is a substance can reduce or relieve pain without removing awareness. Leunca leaf contains flavonoid, alkaloid, saponin and steroid. This research aimed to understand analgetic activity leuncha leaf ethanol extract with tail flick and wrhithing test methode and determining the doses variations of leunca leaf ethanol extract on the activity of analgesic. Leunca leaf was extracted by remaceration method using ethanol 70%. Analgesic activity testing was done using 25 white male rats with tail flick analgesy-meter and stopwatch. The animals model was devided by five groups, group I (CMC-Na), group II (mefenamic acid), group III (leunca leaf ethanol extract 5 mg / 200 g BB), group IV (leunca leaf ethanol extract 10 mg / 200 g BB), group V (leunca leaf extract ethanol extract 20 mg / 200 g BB). The results were measured after 30 minutes peroral granting extract, next were measured performed on 60, 90, and 120 minutes. The resuld showed that leunca leaf ethanol extract had activity analgesic on white malerats . Doses of leunca leaf ethanol extract 20 mg/ 200 g BB; have analgesic activity significan closed to mefenamic acid. Keywords : analgesic, leunca leaf ethanol extract, tail flick analgesy and writhing test

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	analgesic, leunca leaf ethanol extract, tail flick analgesy and writhing test
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Rohma Tri Wardani
Date Deposited:	25 Feb 2019 03:14
Last Modified:	25 Feb 2019 03:14
URI:	http://repo.setiabudi.ac.id/id/eprint/1050

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