UJI AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN SALAM (Eugenia polyantha W.) DAN DAUN MANGGA ARUMANIS (Mangifera indica L.) TERHADAP TIKUS PUTIH JANTAN YANG DIINDUKSI ALOKSAN

Despianty, Rizka (2017) UJI AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN SALAM (Eugenia polyantha W.) DAN DAUN MANGGA ARUMANIS (Mangifera indica L.) TERHADAP TIKUS PUTIH JANTAN YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Salam leaves (Eugenia polyantha W.) and Mangga leaves (Mangifera indica L.) were trust praclinically could decreased blood glucose effectively. The purpose of this study was to determine combine dose of effective salam leaves extract and mangga leaves extract in lowering blood glucose level and dose of combination salam leaves extract and mangga leaves extract coul decreased blood glucose effectively. Forthy rats were divided into eight groups. three groups were control (normal, negative, positive), dose of salam leaves extract was 91,7 mg/kg BW, dose of mangga leaves extract was 147 mg/kg BW, dose combine of salam leaves : mangga leaves 25% : 75% were 22,925 mg/kg BW : 110,25 mg/kg BW, 75% : 25% were 68,755 mg/kg BW : 36,75 mg/kg BW, 50% : 50% were 45,85 mg/kg BW : 73,5 mg/kg BW. Rats were inducted with 150 mg/kg BW by alloxan intraperitoneal. After the glucose levels ± 200 mg/dl, were treatment for 14 days orally. The measurement of glucose at days 0th , 1st ,7th ,14th. Blood samples were analyzed with GOD PAP methods. Glucose levels was analyzed with ANOVA. The result showed that salam leaves extract and mangga leaves extract contained a flavonoid, tanin, and saponin. The result of glucose levels showed that combination salam leaves extract and mangga leaves extract could decreased blood glucose and dose of combination 75% : 25% were 68,755 mg/kg BB : 36,75 mg/kg BB. This combination proportionated with salam leaves single extract but better than mangga leaves single extract. Keyword : alloxan, Eugenia polyantha W., Mangifera indica L., GOD PAP, blood glucose

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	alloxan, Eugenia polyantha W., Mangifera indica L., GOD PAP, blood glucose
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Herera Gadys USB
Date Deposited:	25 Feb 2019 03:22
Last Modified:	25 Feb 2019 03:22
URI:	http://repo.setiabudi.ac.id/id/eprint/1118

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