UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI BUAH BIDARA (Zizyphus mauritiana Lamk.) TERHADAP Staphylococcus aureus ATCC 25923

KURNIAWATI, Rossy (2018) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSANA, ETIL ASETAT, DAN AIR DARI BUAH BIDARA (Zizyphus mauritiana Lamk.) TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The bidara plant known by the Latin name Zizyphus mauritiana Lamk. is a plant that has many benefits in traditional medicine. Bidara is known to have benefits as antioxidant, antimicrobial, antidiarrheal, antidiabetic, hepatoprotective, and anticancer. This study aims to determine the antibacterial activity of ethanol extract, fraction n-hexane, ethyl acetate, and water from the fruit bidara against Staphylococcus aureus ATCC 25923. Fruit bidara was extracted by maceration method with ethanol 70% solvent. The extracts obtained were fractionated with solvents n-hexane, ethyl acetate, and water. Fractionation results were tested for antibacterial activity against Staphylococcus aureus ATCC 25923 using diffusion method with concentrations of 50%, 25%, 12.5% and dilution methods with concentrations of 50%, 25%, 12.5%, 6.25%, 3, 13%, 1.57%, 0.79%, 0.40%, 0.20%, 0.10%. The results showed that ethanol extract, fractions n-hexane, ethyl acetate, and water of bidara had antibacterial activity against bacteria Staphylococcus aureus ATCC 25923. Concentration of 50% of ethyl acetate fraction had the most effective antibacterial activity with inhibitory diameter of 18.67 mm and Minimum Bactericidal Concentration (MBC) of 3,13% against Staphylococcus aureus ATCC 25923. Keywords: bidara (Zizyphus mauritiana Lamk.), Staphylococcus aureus ATCC 25923, antibacterial, fraction n-hexane, ethyl acetate, and water

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: bidara (Zizyphus mauritiana Lamk.), Staphylococcus aureus ATCC 25923, antibacterial, fraction n-hexane, ethyl acetate, and water.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 25 Feb 2019 03:30
Last Modified: 25 Feb 2019 03:30
URI: http://repo.setiabudi.ac.id/id/eprint/1169

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