UJI AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSANA, ETIL ASETAT DAN AIR DARI EKSTRAK ETANOL DAUN ASHITABA (Angelica keiskei (Miq.) Koidz) TERHADAP Streptococcus mutans ATCC 25175

Putri, Luluk Aniqoh Meliana (2017) UJI AKTIVITAS ANTIBAKTERI FRAKSI n-HEKSANA, ETIL ASETAT DAN AIR DARI EKSTRAK ETANOL DAUN ASHITABA (Angelica keiskei (Miq.) Koidz) TERHADAP Streptococcus mutans ATCC 25175. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Ashitaba leaves contained a chemical compounds such as alkaloid, tannins, flavonoid and saponin. This purpose of this study was to determine antibacterial activity of the fraction of n-hexane, ethyl acetate and water from ashitaba leaves extract against Streptococcus mutans ATCC 25175. Ashitaba leaves was extract with ethanol 96% by maceration method. Extract was collected and fractionated with n-hexane, ethyl acetate and water. The result of antibacterial activity with fractination against Streptococcus mutans ATCC 25175 by diffusion method with various concentration (50%, 25%, and 12,5%) for known which the most active of fraction. The most active of fraction was continued with dilution method for known which Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) with concentration of 50%, 25%, 12,5%, 6,25%, 3,125%, 1,562%, 0,781%, 0,391%, 0,195%, 0,098%. The result showed that the fraction of n-hexane, ethyl acetate and water from the extraction of ashitaba leaves had antibacterial activity against Streptococcus mutans ATCC 25175. Concentration of 50% of the fraction ethyl acetate, water had an average diameter were 24 mm. The most effective fraction against Streptococcus mutans ATCC 25175 was ethyl acetate fraction with Minimum Inhibitory Concentration resulted as unknown and Minimum Bactericidal Consentration was 12,5%. Keyword : Angelica keiskei (Miq.) Koidz, antibacterial, fraction, Streptococcus mutans ATCC 25175

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Angelica keiskei (Miq.) Koidz, antibacterial, fraction, Streptococcus mutans ATCC 25175
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Rohma Tri Wardani
Date Deposited: 25 Feb 2019 03:40
Last Modified: 25 Feb 2019 03:40
URI: http://repo.setiabudi.ac.id/id/eprint/1230

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