UJI AKTIVITAS KOMBINASI SERBUK TEMULAWAK (Curcuma xanthorrhiza Roxb) DAN TEMU PUTIH (Curcuma zedoaria (Charistm.) Roscoe) SEBAGAI PENURUN KADAR SGOT DAN SGPT PADA TIKUS JANTAN GALUR WISTAR YANG DIINDUKSI PARASETAMOL

FRASTYA, Zaidy (2018) UJI AKTIVITAS KOMBINASI SERBUK TEMULAWAK (Curcuma xanthorrhiza Roxb) DAN TEMU PUTIH (Curcuma zedoaria (Charistm.) Roscoe) SEBAGAI PENURUN KADAR SGOT DAN SGPT PADA TIKUS JANTAN GALUR WISTAR YANG DIINDUKSI PARASETAMOL. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Powder of Curcuma xanthorrhiza and Curcuma zedoaria contains curcumin compound that has potential as hepatoprotective. This research was conducted to determine the dose of combination Curcuma xanthorrhiza 27 mg/kgbb and Curcuma zedoaria 27 mg/kgbb which is optimal to reduce levels of SGOT and SGPT in male rats strain wistar that induced paracetamol. This research used 18 rats were divided into 6 groups, each 3 rats that is, group I normal control, group II negative control (CMC 0.5%), the positive control group III (Curcuma 3 tablets), group IV were given a dose of Curcuma xanthorrhiza single 54 mg/kgbb, group V dose combination of Curcuma xanthorrhiza 27 mg/kgbb and Curcuma zedoaria 27 mg/kgbb, group VI were given a single dose of Curcuma zedoaria mg/kgbb. All groups were treated for 12 days. On day 13-14 was given paracetamol expect the normal controls. Day 0 and 15 are set SGOT and SGPT. The data obtained were analyzed by One Way Anova. The results showed that dosage of the dose of Curcuma xanthorrhiza single 54 mg/kgbb, dose of combination of Curcuma xanthorrhiza 27 mg/kgbb and Curcuma zedoaria 27 mg/kgbb and a single dose of Curcuma zedoaria 54 mg/kgbb reduce levels of SGOT and SGPT, but dose of combination of Curcuma xanthorrhiza 27 mg/kgbb and Curcuma zedoaria 27 mg/kgbb optimally reduce levels of SGOT and SGPT. Keywords: Curcuma xanthorrhiza Roxb, (Curcuma zedoaria (Charistm.) Roscoe), Paracetamol, SGOT, SGPT.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Curcuma xanthorrhiza Roxb, (Curcuma zedoaria (Charistm.) Roscoe), Paracetamol, SGOT, SGPT.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	25 Feb 2019 03:42
Last Modified:	25 Feb 2019 03:42
URI:	http://repo.setiabudi.ac.id/id/eprint/1274

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