PENGARUH KOMBINASI TEA DAN CARBOPOL® 940 TERHADAP MUTU FISIK GEL ANTIOKSIDAN DAUN MANGGIS (Garcinia mangostana L.) DENGAN METODE DESIGN FACTORIAL

AYUNINGSIH, Deasy Putri (2016) PENGARUH KOMBINASI TEA DAN CARBOPOL® 940 TERHADAP MUTU FISIK GEL ANTIOKSIDAN DAUN MANGGIS (Garcinia mangostana L.) DENGAN METODE DESIGN FACTORIAL. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Mangosteen extract as an antioxidant because it contains xanthones in large quantities.The use of the extract directly less practical, so the gel formulation.The addition of TEA and are used as a base Carbopol gelling. This study aims to determine the physical influence of the leaf extract of mangosteen by using two of additives of TEA and Carbopol by factorial design method. Mangosteen leaf extract obtained by maceration using 70% ethanol is then evaporated to obtain a thick extract. Mangosteen extract gel was made in four formulas of tea and Carbopol combination with various concentrations. The resulting gel was tested physical properties include organoleptic, viscosity, dispersive power, duration and the inherent antioxidant activity for 21 days.To determine the effect of the combination of TEA and Carbopol using Ease® desigen software version 8.0.6.1. Results showed that Carbopol gel can increase the viscosity and stickiness of the gel, but decrease the scatter gel, while the increase of the spread gel TEA.The antioxidant activity of mangosteen extract gel obtained IC50 is 88,511, 88,715, 86,496, 89,125 ppm. Keywords: mangosteen extract gel, antioxidant, factorial design

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	mangosteen extract gel, antioxidant, factorial design
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Sep 2019 02:20
Last Modified:	30 Sep 2019 02:20
URI:	http://repo.setiabudi.ac.id/id/eprint/1337

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