UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOLIK DAUN PLETEKAN (Ruellia tuberosa L.) PADA AYAM LEGHORN JANTAN

RAHMADHANNY, Depridar Dwi (2016) UJI AKTIVITAS ANTIHIPERURISEMIA EKSTRAK ETANOLIK DAUN PLETEKAN (Ruellia tuberosa L.) PADA AYAM LEGHORN JANTAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Pletekan plants (Ruellia tuberosa L.) was one of the folk medicines that approximately has an effect to decrease the level of uric acid. This research aims to determine the effect of ethanolic extract of pletekan and the most effective dose as reduce the level of uric acid. This research was conducted 24 leghorn cocks were divided into 6 group. Group I as positive control was given allopurinol 7mg/1,5kg bw, group II as negative control was given CMC 0,5%, group III as normal control, group IV, V, VI as treatment groups were given of ethanolic extract of pletekan leaves doses 206,25mg/1,5kg bw; 412,5mg/1,5kg bw; 825mg/1,5kg bw; respectively. The treatment has been conducted for 14 days. Blood sampling was held three times at the 0, 7th, and 14th day. The level of uric acid was measured using spectrophotometer. The results were analyzed using one-way ANOVA (significance level > 0,05). The results showed that all dose of ethanolic extract of pletekan leaves able to reduce the level of uric acid. Extract in dose 825mg/1,5kg bw is the most effective dose could reduce the level of uric acid as well as allopurinol. Key words: pletekan (Ruellia tuberosa L.), hyperuricemia, leghorn cock, allopurinol.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: pletekan (Ruellia tuberosa L.), hyperuricemia, leghorn cock, allopurinol.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 30 Sep 2019 03:36
Last Modified: 30 Sep 2019 03:36
URI: http://repo.setiabudi.ac.id/id/eprint/1341

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