AKTIVITAS ANTIBAKTERI KOMBINASI FRAKSI ETIL ASETAT DARI EKSTRAK ETANOL DAUN KAPUK RANDU (Ceiba pentandra Gaertn) DAN KOTRIMOKSAZOL TERHADAP Staphylococcus aureus ATCC 25923 BESERTA BIOAUTOGRAFI

RAHMAWATI, Dessi (2016) AKTIVITAS ANTIBAKTERI KOMBINASI FRAKSI ETIL ASETAT DARI EKSTRAK ETANOL DAUN KAPUK RANDU (Ceiba pentandra Gaertn) DAN KOTRIMOKSAZOL TERHADAP Staphylococcus aureus ATCC 25923 BESERTA BIOAUTOGRAFI. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Infectious diseases are diseases caused by microbes one of which is Staphylococcus aureus. Staphylococcus aureus is a normal flora of the mucous layer of the human body. The condition that decreases the body's defenses can cause these bacteria to grow and cause disease. Staphylococcus aureus are resistant to multiple antibiotics. The purpose of this study to determine the antibacterial activity of a combination of ethyl acetate fraction of ethanol extract of cottonwood leaves with cotrimoxazole against Staphylococcus aureus ATCC 25923. Kapok leaf extracted by 70% ethanol and fractionated by ethyl acetate. Antibacterial testing is done to determine the disk diffusion inhibition zone. The concentration of ethyl acetate fraction of cottonwood leaves ethanol extract of 12.5% and 0.038% of co-trimoxazole. Comparison of a combination of ethyl acetate fraction of ethanol extract of cottonwood leaves and cotrimoxazole: 1: 9; 2: 8; 3: 7; 7: 3; 8: 2; and 9: 1. The test results by comparison of antibacterial activity of a combination of ethyl acetate fraction of ethanol extract of cottonwood leaves and cotrimoxazole against Staphylococcus aureus showed the ratio of 1: 9 and 2: 8 has the same activity with cotrimoxazole. Inhibition zone diameter of a ratio of 1: 9 and 2: 8 of 20.5 mm and 18.67 mm. Based on the results of statistical analysis of the ratio of 1: 9 and 2: 8 not significantly different with cotrimoxazole . Keywords: Ceiba pentandra Gaertn, Cotrimoxazole, Staphylococcus aureus, disk diffusion

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Ceiba pentandra Gaertn, Cotrimoxazole, Staphylococcus aureus, disk diffusion
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	30 Sep 2019 03:37
Last Modified:	30 Sep 2019 03:37
URI:	http://repo.setiabudi.ac.id/id/eprint/1342

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