EL HASANI, Abdul Majid (2016) FORMULASI NUTRASETIKAL SEDIAAN GUMMY CANDIES EKSTRAK ETANOL DAUN KELOR (Moringa oleifera Lamk.) DENGAN VARIASI KADAR MANITOL - GELATIN. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Moringa leaves (Moringa oleifera Lamk.) is a plant that is useful as immunomodulation that contain coumpounds such as flavonoids like quercetin and cathecin, polyphenols like tannin, and terpenoids like vitamin A and β-caroten. This study was aimed to produce a gummy candies dosage form of moringa leaves extract with variations concentration of mannitol as a sweetener agent and gelatin as a gelling agent or chewy agent that are qualified to physical quality and suitable to kids. Moringa leaves extract that was obtained from maceration using 70% ethanol was made into 5 formulas of gummy candies with variations concentration of mannitol-gelatin in a row of 50: 50%, 40: 60%, 25: 75%, 60: 40%, 75: 25%. Preparations were made with an average weight of 3.3 grams at a dose of 200 mg extract. Physical test of dosage form was conducted on the organoleptic test, pH test, weight uniformity test, moisture content test, elasticity test and stability test of dosage forms. Phytochemical content quality test of dosage form using test tubes and preference level of the dosage form involved from 20 kid respondents. Results of the analysis showed that the extract of moringa leaves could be made gummy candies with variations concentration of mannitol-gelatin and obtained the best formula is formula 3 that was preferred by kids. Variations concentration of mannitol-gelatin can influence the physical properties which of a higher level of mannitol preparation impacted more sweet and lower the elasticity of dosage forms while the higher levels of gelatin impacted more rubbery and higher elasticity of dosage form. Keywords: Moringa leaf extract, gummy candies, gelatin, mannitol, physical quality test
Item Type: | Thesis (Skripsi) |
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Uncontrolled Keywords: | Moringa leaf extract, gummy candies, gelatin, mannitol, physical quality test |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
Depositing User: | Tifany Nur Arfiana |
Date Deposited: | 30 Sep 2019 04:03 |
Last Modified: | 30 Sep 2019 04:03 |
URI: | http://repo.setiabudi.ac.id/id/eprint/1344 |
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