FEBRIANA, Laela (2016) PENGARUH PEMBERIAN KOMBINASI EKSTRAK DAUN SIDAGURI (Sida rhombifolia L.) DENGAN DAUN KUMIS KUCING (Orthosiphon aristatus (Bl) Miq.)TERHADAP PENURUNAN KADAR ASAM URAT PADA AYAM LEGHORN. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Sidaguri and kumis kucing leaves have activity anti-hyperuricemia. This study aims to determine the effect of the combination extract of sidaguri leaves (Sida rhombifolia L.) and kumis kucing leaves (Orthosiphon aristatus (Bl) Miq.) to decrease uric acid levels in leghorn chickens. The study used 35 chickens were divided into 7 groups. Group I: ethanolic extract of sidaguri leaves 27,8mg/1,5 kg, group II: the leaf extract of kumis kucing leaves 81,18mg/1,5 kg bb. Group III, IV, V given a combination of ethanolic extracts sedaguri and kumis kucing leaves in a row (75%:25% or 20,85mg /1,5 kg bb:20,295mg/1,5 kg bb); (50%:50% or 13,9mg/1,5 kg bb:40,59mg/1,5 kg bb); (25%:75% or 6,95mg/1,5 kg bb:60,885mg/1,5 kg bb). Group VI: negative control (CMC 0,5%) and Group VII: positive control (Allopurinol) 14mg/1,5 kg bb. The treatment was done for 14 days. During the 7 days all groups in order chicken liver juice induced hyperuricemia, and all groups were given the test preparation except negative control. Blood sampling performed 3 times (0th, 7th and 14th) uric acid levels were measured with a spectrophotometer. The data obtained were analyzed by One Way Anova (p> 0.05), continued of SNK test. The results showed that the ethanolic extract sidaguri and kumis kucing leaves have ability to lower uric acid levels and combinations of ethanolic extract 50%:50% (13,9mg/1,5 kg bb:40,59mg/1,5 kg bb) lowering uric acid levels greatest. Keywords: ethanolic extract, sidaguri leaves, kumis kucing leaves, allopurinol, hyperuricemia.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | ethanolic extract, sidaguri leaves, kumis kucing leaves, allopurinol, hyperuricemia. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 01 Oct 2019 03:14 |
| Last Modified: | 01 Oct 2019 03:14 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/1397 |
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