FORMULASI TABLET KUNYAH EKSTRAK KULIT BUAH NAGA SUPER MERAH (Hylocereus costaricencis) SEBAGAI ANTIOKSIDAN DENGAN KOMBINASI MANITOL DAN CMC-Na

SETYANINGSIH, Aninda Tri Is (2015) FORMULASI TABLET KUNYAH EKSTRAK KULIT BUAH NAGA SUPER MERAH (Hylocereus costaricencis) SEBAGAI ANTIOKSIDAN DENGAN KOMBINASI MANITOL DAN CMC-Na. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Super red dragon fruit peels (Hylocereus costaricensis) are waste contain that many antioxidant compounds, namely polyphenols and flavonoids. The study was aimed to know the effect of the combination of mannitol and CMC-Na on the physical properties and antioxidant activity in formulation of chewing tablet super red dragon fruit peels extract. Super red dragon fruit peels extract was obtained by maceration using ethanol 70%. Then the extract were made into 5 formula chewing tablet with combination of mannitol and CMC-Na, i.e. : 40%:6%; 47,5%:5,25%; 55%:4,5%; 62,5%:3,75%; 70%:3%. The tablets were made in weight 1.500 mg. Chewing tablet evaluation were done on the physical tested including weight uniformity, hardness, friability, taste perception, disintegration, and antioxidant activity by DPPH method. The data was analyzed by SPSS Statistic version 17.0 using one way Anova. The results indicated that the antioxidant activity in chewing tablet super red dragon fruit peels extract and the combination of mannitol and CMC-Na were effected on the physical property test of tablet and taste perception from chewing tablet super red dragon fruit peels extract. Key Words: chewing tablet, super red dragon fruit peels, mannitol, CMC-Na.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: chewing tablet, super red dragon fruit peels, mannitol, CMC-Na.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Oct 2019 03:34
Last Modified: 01 Oct 2019 03:34
URI: http://repo.setiabudi.ac.id/id/eprint/1530

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