UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL 70% BIJI LADA HITAM (Piper nigrum L. ) DAN DAUN PEGAGAN (Centella asiatica L. Urban) TERHADAP BAKTERI Escherichia coli ATCC 25922

PRIMANANDA, Arina Zulfah (2015) UJI AKTIVITAS ANTIBAKTERI KOMBINASI EKSTRAK ETANOL 70% BIJI LADA HITAM (Piper nigrum L. ) DAN DAUN PEGAGAN (Centella asiatica L. Urban) TERHADAP BAKTERI Escherichia coli ATCC 25922. Skripsi thesis, Universitas Setia Budi Surakarta.

	Text ABSTRAK.pdf Download (88kB)
	Text 2015-17113239A.pdf Restricted to Repository staff only Download (3MB) | Request a copy

Abstract

Seeds of black pepper (Piper nigrum L) and leaves of gotu kola (Centella asiatica L. Urban) have antimicrobial compounds are efficacious for treating diarrhea. This study aims to determine the activity of the combination of black pepper seed extract and gotu kola leaves in varying ratios and combinations to find the most effective comparison of the three comparisons that combination. Seeds of black pepper and leaves of gotu kola extracted using maceration method. A combination of 70% ethanol extract of black pepper seeds and leaves of gotu kola made the series a concentration of 100 mg / ml; 50 mg / ml; 25 mg / ml; 12,5mg / ml; 6.25 mg / ml; 3.125 mg / ml; 1.565 mg / ml; 0.781 mg / ml; 0.3905 mg / ml; negative control, and positive control with three combinations of concentration, namely (1: 1); (1: 2); (2: 1) and cotrimoxazole as controls for comparison. Tests conducted on the bacteria Escherichia coli ATCC 25 922 in dilution. Antibacterial test results showed the combination of extracts have antibacterial activity against Escherichia coli ATCC 25 922 on a comparison of the combination (1: 1) and (2: 1) to minimum bactericidal concentration (MBC) of 100 mg / ml and 50 mg / ml. Comparison of the most effective combination that is (2:1) because the concentration of black pepper seeds are larger and contains flavonoids, alkaloids, tannins, saponins, essential oils, and piperine while gotu kola leaves contain flavonoids, alkaloids, tannins, saponins, and glycosides triterpen. Keywords: Seeds of black pepper (Piper nigrum L), gotu kola leaf (Centella asiatica L. Urban), Escherichia coli ATCC 25922, antibacterial,

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Seeds of black pepper (Piper nigrum L), gotu kola leaf (Centella asiatica L. Urban), Escherichia coli ATCC 25922, antibacterial,
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	01 Oct 2019 03:34
Last Modified:	01 Oct 2019 03:34
URI:	http://repo.setiabudi.ac.id/id/eprint/1531

Actions (login required)

View Item