FORMULASI GEL ANTIOKSIDAN DARI EKSTRAK UMBI WORTEL (Daucus Carota L.) DENGAN MENGGUNAKAN CARBOPOL® 940

ASYHARI, Hanif Fibiana (2015) FORMULASI GEL ANTIOKSIDAN DARI EKSTRAK UMBI WORTEL (Daucus Carota L.) DENGAN MENGGUNAKAN CARBOPOL® 940. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Carrot is one plant that has been proves to have antioxidant activity due to its carotenoids content. This study was aimed to find out whether carrot root extract could be made gel preparation and had antioxidant activity. Carrot not extract was obtained by juice method, and then condensed with rotary evaporator. The gels were made in 5 formulas where in formula 1, 2, and 3 contained 5%, 10%, and 15% carrot extract respectively. Formula 4 was negative control (without active substance) and formula 5 was positive control (contain rutin). The antioxidant activity was tested by DPPH method, and observed its physical properties including homogeneity, dispersive, adhesiveness. Viscosity, and pH. The result of the study showed that carrot extract could be made gel preparation in various concentrations and had good homogeneity. The higher the extract concentration in gel, it produced small viscosity and dispersive values, but great adhesiveness. The IC50 value of carrot root extract was 506.991 ppm. The formula 1, 2, and 3 were 749.894 ppm, 714.496 ppm, and 680.769 ppm respectively. Those results showed there were differences in antioxidant activity of carrot extract before and after being made gel preparation and after 21 days storage. Keywords: carrot root extract, gel, antioxidant.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: carrot root extract, gel, antioxidant.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Oct 2019 03:38
Last Modified: 01 Oct 2019 03:38
URI: http://repo.setiabudi.ac.id/id/eprint/1554

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