UJI AKTIVITAS ANTIBAKTERI EKSTRAK BIJI PEPAYA (Carica papaya L.) TERHADAP Vibrio cholerae SECARA DIFUSI

KRISNAWATI, NANIK (2016) UJI AKTIVITAS ANTIBAKTERI EKSTRAK BIJI PEPAYA (Carica papaya L.) TERHADAP Vibrio cholerae SECARA DIFUSI. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Papaya seed was reported to have medicinal properties as worm and diarrhea drugs and in its many contain alkaloids, flavonoids, saponins, tannins. Vibrio cholerae is one of the bacteria that cause diarrhea. This study was aimed to test the antibacterial activity of papaya seed extract against Vibrio cholerae. Papaya seed extract obtained by maceration using ethanol 70%. Dilution of papaya seed extract made in various concentrations (25%, 50%, 75%, 100%). Test of Antibacterial activity was carried out by diffusion method to determine the zone radical diameter against Vibrio cholerae. Class of active compound contained in papaya seed extract after testing qualitatively, Papaya seed extract contains active compounds, namely, flavonoid which has the function of disturbing the cytoplasmic membrane, saponin with destabilizing the bacterial cell membrane and tannin is useful to inactivate the enzyme and disrupt transport protein on the inner lining cell. The results showed papaya seed extract at concentrations of 25%, 50%, 75%, 100% indicate there was radical zone to growth of Vibrio cholerae. The amount of antibacterial activity of papaya seed extract at all concentrations was real difference. So the administration of papaya seed extract concentrations of 25%, 50%, 75%, 100% was proven to have antibacterial activity against Vibrio cholerae and at concentration 100% showed the most extensive broad inhibition zone 15.67 mm. Keywords: extract, seed, papaya, antibacterial, Vibrio cholerae

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: extract, seed, papaya, antibacterial, Vibrio cholerae
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Ilmu Kesehatan > Prodi D3 Analis Kesehatan
Depositing User: magdalena kartika ningsih
Date Deposited: 09 Oct 2019 08:18
Last Modified: 09 Oct 2019 08:18
URI: http://repo.setiabudi.ac.id/id/eprint/1681

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