The Differences of Mean Platelet Volume of Acute Myocardial Infarction Patients with and without Type II Diabetes Mellitus at Rumah Sakit Umum Daerah Dr. Moewardi, Surakarta

Nurkhotimah, Hartin (2018) The Differences of Mean Platelet Volume of Acute Myocardial Infarction Patients with and without Type II Diabetes Mellitus at Rumah Sakit Umum Daerah Dr. Moewardi, Surakarta. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Acute Myocardial Infarction (IMA) is a continued situation of myocardium ischemia mechanism which is generally caused by a totally coronary arteries blockage under insufficient condition. Collateral system itself does not work properly, thus it could affect in partially myocardium degradation. Meanwhile, Diabetes Mellitus (DM) is a hyperglycemic situation or the disruption of fats, carbohydrates, and proteins metabolism in the body which are associated absolutely or relatively of insulin deficiency in term of its secretions and activities. Other term, Mean Platelet Volume (MPV) refers to thrombocytes or platelets activities and its functions in the body. Large size of platelets represents the average volume of platelet granules which indicate more dense and reactive in DM. This study aims to understand whether any differences of MPV in IMA patients with and without DM. An analytical observation with cross-sectional approach was performed as the method of this study. Targeted population for sampling were IMA patients who have DM and non-DM history and examined their MPV at Pathological Clinic Laboratory, Rumah Sakit Umum Daerah Dr. Moewardi, Surakarta within 2014-2018. Secondary data were used which were collected from medical records. An analysis was conducted using computer program by independet sample t-test with 95% confidence level. The mean outcomes of ± SD MPV levels in IMA patients with DM (8.487 ± 1.3211) were higher than mean ± SD of non-DM IMA patients (8,413 ±1,0628). Based on the results of research and analysis of MPV data on IMA patients with history of DM and non-DM it can be concluded that there is no significant difference to MPV levels in IMA patients with history of DM and non-DM. Further research needs to be done on what factors affect the increase or decrease in MPV levels Based on thorough analyses, it can be concluded that there is no significant difference of MPV levels between IMA patients with DM and without DM. Further research needs to be done on what factors affect the increase or decrease in MPV levels. Keywords: acute myocardial infarction, diabetes mellitus, mean platelet volume

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	acute myocardial infarction, diabetes mellitus, mean platelet volume
Subjects:	R Medicine > R Medicine (General)
Divisions:	Fakultas Ilmu Kesehatan > Prodi D4 Analis Kesehatan
Depositing User:	magdalena kartika ningsih
Date Deposited:	22 Feb 2019 08:02
Last Modified:	22 Feb 2019 08:02
URI:	http://repo.setiabudi.ac.id/id/eprint/176

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