KUSUMAWATI, Anas Diah (2015) PENGARUH PEMBERIAN KOMBINASI EKSTRAK ETANOL DAUN BAWANG KUCAI (Allium tuberosum Rottl ex. Spreng) DAN KELOPAK BUNGA ROSELLA (Hibiscus sabdarifa L.) TERHADAP KADAR KOLESTEROL TOTAL PADA TIKUS JANTAN GALUR WISTAR. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
The plants having total cholesterol lowering activity among others are bawang kucai leaves and rosella flower calyx. The objective of research was to find out effectiveness, effective doses, and pharmacodynamic interaction property of combined bawang kucai leaves and rosella flower calyx ethanol extracts compared with single dose on total cholesterol lowering in wistar strain male rat. The method of extracting simplicia used was maceration with ethanol 70%. About 35 rats were divided into 7 groups. Group 1 was healthy, group 2 sick, group 3(rosella flower calyx extract of 100 mg/200 BW), group 4(bawang kucai leaves extract of 22 mg/200g Bw), group 5 bawang kucai leaves and rosella flower calyx extracts(1/2:1/2), group 6 rosella flower calyx and bawang kucai leaves extracts(1/4:3/4)), group 7 rosella flower calyx and bawang kucai leaves extracts(3/4:1/4) induced with high fat first for 14 days. The data total cholesterol lowering was analyzed using One-way Anova, followed with Post-Hoc test. The result of study showed the combination of bawang kucai leaves and rosella flower calyx ethanol extracts lowered the total cholesterol level more effectively compared with single dose with combined dose (11mg/200gBW and 50mg/200gBW) and provided synergic pharmacodynamic interaction properties on lowering the total cholesterol level of wistar strain male rat. Keywords: bawang kucai leaves, rosella flower calyx, total cholesterol
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | bawang kucai leaves, rosella flower calyx, total cholesterol |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Mrs NOVI HANDAYANI |
| Date Deposited: | 10 Oct 2019 08:35 |
| Last Modified: | 10 Oct 2019 08:35 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/1980 |
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