MAHMUDAH, Dinda Nur (2015) UJI AKTIVITAS KOMBINASI EKSTRAK ETANOL DAUN BAWANG KUCAI (Allium tuberosum Rottl.ex spreng) dan KELOPAK BUNGA ROSELLA (Hibiscus sabdariffa L.) TERHADAP PENURUNAN KADAR TRIGLISERIDA pada TIKUS HIPERLIPIDEMIA. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Onion leaf chives and rosella flower petals from previous research that antihiperlipidemia activity. This research aimed to combinations of ethanol extract of green onion chives and rosella flower petals have an activities more effective than a single dose of the combination effectively lowers triglyceride levels and the nature of the interaction pharmacodynamics of the combination of the extract to lower triglyceride levels in male rats. Animals were divided into 7 groups. The healthy control group I, group II control pain (hypertriglyceridemia), group III ethanol extract of green onion chives 22 mg / 200 g bw IV group rosella flower petals ethanol extract 100 mg / 200 g bw combination I group V, group VI combination Ii, group VII combination III. All test animals unless the healthy controls given a high-fat diet for 14 days, beginning the 15th day of test animals is given in accordance with the group treated once daily for 7 days. Testing levels of triglycerides using GPO - PAP seen on day 7, 14 and 21. Data were analyzed using the Kolmogorov - Smirnov test was continued one- way ANOVA. The results of research showed that administration of a combination of ethanol extract of green onion chives and rosella flower petals can lower blood serum triglyceride levels of mice. The effective dose lowering triglyceride levels at doses each half of the effective dose (11 mg : 50 mg ) or a combination of the first group were significantly ie 86.2 mg / dL and the nature of this interaction pharmacodynamics on the synergistic. Keywords : ethanol extract of leaves of onion chives and rosella flower petals, antihipertrigliserida, white male rats.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | ethanol extract of leaves of onion chives and rosella flower petals, antihipertrigliserida, white male rats. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Mrs NOVI HANDAYANI |
| Date Deposited: | 14 Oct 2019 04:27 |
| Last Modified: | 14 Oct 2019 04:27 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/2008 |
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