EFEK EKSTRAK ETANOL 70% DAUN SARANG SEMUT (Hydnophytum Formicarum Jack.) TERHADAP KADAR LDL DAN HDL PADA SERUM DARAH TIKUS PUTIH JANTAN

BERE, Maria Erosvita (2015) EFEK EKSTRAK ETANOL 70% DAUN SARANG SEMUT (Hydnophytum Formicarum Jack.) TERHADAP KADAR LDL DAN HDL PADA SERUM DARAH TIKUS PUTIH JANTAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Hyperlipidemia was increase concentration of all lipids an plasma include triglyceride, cholesterol, and is usually characterized by increase LDL level and decrease HDL level. Traditional medicine was treat this disease can use ant plant (Hydnophytum formicarum Jack.). The purpose of this study was to determine effect ethanol 70% extract of ant plant leaves to LDL and HDL levels of white male rat, and determine the most effective dose. Ant plant pollen leaves powder 500 grams was macerated with 70% ethanol. Male white rats were divided into six groups, each 5 rats. Group 1st normal control (no treatment), Group 2nd negative control were given high fat diet, Group 3rd positive control were given simvastatin suspension 0,018 mg/200 g BW rat, Group 4th, Group 5th, Group 6th were given variation of ant plant leaves doses 18 mg / 200 g BW rat, 36 mg/200 g BW rat, 72 mg/200 g BW rat. Then measurement LDL and HDL levels on blood serum of white male rat days 0, 14, and 21 used the CHOD-PAP method. Data analyze used Paired Samples T-Test and Two Way Anova. The results showed that 70% ethanol extract of ant plant leaf had effect on HDL and LDL levels of rat had given high-fat diet. The dose 70% ethanol of ant plant leaf extract way most effective in lowering LDL levels and increase HDL level was the third dose 72 mg/200 g BW of rats. Keywords: hyperlipidemia, ant plant, HDL, LDL

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: hyperlipidemia, ant plant, HDL, LDL
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 21 Feb 2020 03:44
Last Modified: 21 Feb 2020 03:44
URI: http://repo.setiabudi.ac.id/id/eprint/2242

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