UJI AKTIVITAS ANTIHIPERURISEMIA INFUSA TEMU KUNCI (Boesenbergia pandurata (Roxb.) Schlechter) PADA AYAM LEGHORN JANTAN

NURHARDINI, Maydi Ayu (2015) UJI AKTIVITAS ANTIHIPERURISEMIA INFUSA TEMU KUNCI (Boesenbergia pandurata (Roxb.) Schlechter) PADA AYAM LEGHORN JANTAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Hyperuricemia is a condition when the level of uric acid in blood is shown higher than its normal limit. One of the folk medicines that approximately has an effect to decrease the level of uric acid is fingerroot (Boesenbergia pandurata (Roxb.) Schlechter). The aim of this study was to determine the effect and the optimum dose of infuse of fingerroot to reduce the level of uric acid in leghorn cocks hyperuricemia. This research was conducted using 30 leghorn cocks. The leghorn cocks were induced with 100% w/v chicken liver juice for seven days, except the control normal group. Animals model were divided into six groups, each group consist of 5 cocks. Group I as positive control was given allopurinol 4.67 mg/kgs bw. Group II as a negative control was given CMC 0.5%. Group III, IV, and V as treatment groups were given infuse of fingerroot doses 0.425; 0.85; and 1.7 g/kgs bw, respectively. Group VI is a normal control. The treatment was given for seven days. Blood sampling was held three times at the 0, 7th and 14th day. The blood samples were collected from vena lateralis. The level of uric acid was measured using spectrophotometer Stardust FC*15. The results were analyzed using one-way ANAVA (significance level > 0.05). The results showed that positive control group and the other groups of infuse of fingerroot able to reduce the level of uric acid. The reduction level of uric acid was in proportion to the dose of fingerroot infuse. The optimum dose in this study was 1.7 g/kg due to showed the highest reduction of uric acid level. Keywords : fingerroot (Boesenbergia pandurata (Roxb.) Schlechter), infuse, hyperuricemia, leghorn cock, allopurinol

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	fingerroot (Boesenbergia pandurata (Roxb.) Schlechter), infuse, hyperuricemia, leghorn cock, allopurinol
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Mrs NOVI HANDAYANI
Date Deposited:	21 Feb 2020 03:43
Last Modified:	21 Feb 2020 03:43
URI:	http://repo.setiabudi.ac.id/id/eprint/2250

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