AKTIVITAS STABILISASI MEMBRAN SEL DAN PENGHAMBATAN DENATURASI PROTEIN EKSTRAK ETANOL BIJI WALUH (Cucurbita moschata D.) SECARA IN VITRO

Frestiana, Dia (2014) AKTIVITAS STABILISASI MEMBRAN SEL DAN PENGHAMBATAN DENATURASI PROTEIN EKSTRAK ETANOL BIJI WALUH (Cucurbita moschata D.) SECARA IN VITRO. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Rheumatoid arthritis is a major ailment among rheumatic disorders. A large number of herbal extracts are in vogue used for treatment of various types of rheumatic disorders. Cucurbita moshata D was reported to have antiinflammatory as well as analgesic activity. The qualitative phyto-chemical screening showed the presence of steroids, flavonoids and saponins. The aim of this study was to determine the anti-inflammatory effect of ethanolic extract of the Cucurbita moschata D.by evaluating from the percentage membrane stabilization and percentage inhibition of protein denaturation. The various concentration i.e. 50 to 250 ppm ethanolic extract of the Cucurbita moschata D were prepared. Diclofenac sodium was used as the positive control. These data were analyzed by Independent t-test. The maximum percentage membrane stabilization and inhibition of protein denaturation was found to be 71,58%, and 75,81% respectively at a concentration of 250 ppm. There is no statistically differences between group ethanolic extract of the Cucurbita moschata D and diclofenac sodium. Key Words : Cucurbita moschata D., Protein denaturation, HRBC membran stabilization

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Cucurbita moschata D., Protein denaturation, HRBC membran stabilization
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 18 Feb 2020 06:21
Last Modified: 18 Feb 2020 06:21
URI: http://repo.setiabudi.ac.id/id/eprint/2308

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