FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN PASTA GIGI EKSTRAK DAUN SIRIH MERAH (Piper crocatum (Lmk.) Ruiz. & Pav.) TERHADAP Streptococcus mutans (ATCC 25175) SECARA in vitro

UTOMO, Petrus Wahyu (2015) FORMULASI DAN UJI AKTIVITAS ANTIBAKTERI SEDIAAN PASTA GIGI EKSTRAK DAUN SIRIH MERAH (Piper crocatum (Lmk.) Ruiz. & Pav.) TERHADAP Streptococcus mutans (ATCC 25175) SECARA in vitro. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

The red piper betel plants in additional to be used as ornamental plants is also one of effective antibacterial medicine plants. This study was aimed to find out the influence of red piper betel leaf extract variation on the physical stability and antibacterial activity. The red betel leaf extract was obtained through maseration method using aethanol 70%. Toothpaste preparations were made in 3 formulas, which 1st formula contained 5% extract, 2nd formula contained 10% extract and 3rd formula contained 15% extract. Antibacterial activity test using dilution method and physical stability test including physical form, homogeneity, pH, spreading and viscosity. The results showed that the tootpaste of extract from red betel leaf in various concentrations had good homogeneity. Red piper betel leaf extract toothpaste preparation had pH around 5-6. The higher the concentration of extract in tootpaste produced the smaller viscosity, but spreading getting bigger. The results of antibacterial activity test of tootpaste showed minimum bactericidal concentration 1st and 2nd formula were 12,5%, and 3rd formula was 6,25%. Keywords: red betel leaf extract, tootpaste, physical stability test, antibacterial activity test, dilution.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: red betel leaf extract, tootpaste, physical stability test, antibacterial activity test, dilution
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 21 Feb 2020 03:21
Last Modified: 21 Feb 2020 03:21
URI: http://repo.setiabudi.ac.id/id/eprint/2355

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