Fristica, Mick Sella (2014) UJI EFEK ANTIHIPERGLIKEMIK KOMBINASI EKSTRAK ETANOLIK DAUN SALAM (Eugenia polyantha Wight) DAN DAUN JAMBU BIJI (Psidium guajava L.) PADA MENCIT JANTAN YANG DIINDUKSI ALOKSAN. Skripsi thesis, Universitas Setia Budi Surakarta.
![[img]](http://repo.setiabudi.ac.id/style/images/fileicons/text.png) |
Text
01. INTISARI.pdf Download (219kB) |
|
Text
02. HALAMAN JUDUL - BAB I.pdf Download (495kB) |
|
Text
03. BAB II.pdf Restricted to Repository staff only Download (216kB) | Request a copy |
|
Text
04. BAB III.pdf Restricted to Repository staff only Download (212kB) | Request a copy |
|
Text
05. BAB IV.pdf Restricted to Repository staff only Download (288kB) | Request a copy |
|
Text
06. BAB V - LAMPIRAN.pdf Download (1MB) |
Abstract
Bay (Eugenia polyantha Wight) and guava (Psidium guajava L.) leaves are part of plants which used as antidiabetic drug. This study was aimed to determine effect and dose combination of bay leaf and guava leaf ethanolic extracts which equal with positive control (glibenclamide) in blood glucose level decrease in alloxan-induced mice. The study was conducted using 35 white male mice, swiss, age 3-4 months, weight 20-30 grams. Mice were made diabetic using alloxan by intraperitoneal. All mice were divided 7 groups, each consisting 5 mice which include group I: negative control (CMC 0,5%), group II: positive control (glibenclamide), group III: bay leaf extract (2.62 mg/20 g bb), group IV: guava leaf extract (0.7 mg/20 g bb), and 3 combination groups of bay leaf and guava leaf extracts (1,96 mg/20 g bw:0,87 mg/20 g bw; 1,31 mg/20 g bw:1,75 mg/20 g bw; 0,65 mg/20 g bw:2,62 mg/20 g bw). Blood glucose levelswere observed on 3rd, 7th, and 14th days, measured with GlucoDr glucometer. The blood glucose levels were analyzed by one way ANOVA (p < 0.05), followed by post hoc test. The research result was showed dose administration of combination of bay leaf and guava leaf could lower blood glucose level in mice which induced alloxan. All combination doses of bay leaf and guava leaf extracts (1,96 mg/20 g bw: 0,87 mg/20 g bb; 1,31 mg/20 g bw: 1,75 mg/20 g bb; 0,65 mg/20 g bw: 2,62 mg/20 g bw) gave equal effect with glibenclamide in alloxan-induced male mice. Keywords : Eugenia polyantha Wight, Psidium guajava L, alloxan, blood glucose
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Eugenia polyantha Wight, Psidium guajava L, alloxan, blood glucose |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 19 Feb 2020 07:34 |
| Last Modified: | 19 Feb 2020 07:34 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/2550 |
Actions (login required)
 |
View Item |
