PENGARUH PEMBERIAN EKSTRAK ETANOL 96% DAUN MATOA (Pometia pinnataJ.R. & G. Forst) TERHADAP KADAR GLUKOSA DARAH MENCIT PUTIH JANTAN (Mus musculus) YANG DIBERI BEBAN GLUKOSA

Widayanti, Rizki Tri (2014) PENGARUH PEMBERIAN EKSTRAK ETANOL 96% DAUN MATOA (Pometia pinnataJ.R. & G. Forst) TERHADAP KADAR GLUKOSA DARAH MENCIT PUTIH JANTAN (Mus musculus) YANG DIBERI BEBAN GLUKOSA. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Adult patients with diabetes mellitus continues to increase with increasing levels of affluence and changing lifestyles. Treatment of diabetes mellitus using conventional medicine, is relatively expensive and can cause undesirable side effects. Accordingly, treatment of diabetes switched to traditional medicine. One alternative medicine as an antidiabetic effect as the leaves mellitus is matoa The purpose of this study was to determine the effect of ethanol extract of mangosteen rind to the decline in blood glucose levels. This research method using glucose tolerance by means of test animals fasted for 16 hours, the blood sugar levels checked early (T0), after it is subjected to load glucose and treated with 5-minute intervals, namely group I was the control group (1% CMC) , second group is the comparison group (Glibenclamide), group III (ethanol extract of leaves matoa mg/20gBB 2.8), group IV (ethanol extract of leaves matoa mg/20gBB 5.6), and group V (ethanol extract of leaves matoa 8.4 mg / 20Gbb), and then examined blood glucose levels in minutes 30,60,90, and 120. Results Data were analyzed by one-way ANOVA test followed SNK test at 95% confidence level. The results obtained from this study is that the ethanol extract of leaves matoa (Pometia pinnata JR Forst & G) to provide a blood glucose-lowering effect in Swiss strain male mice at doses of 5.6 mg/20Gbb effective. Keywords: leaf matoa (Pometia pinnata JR Forst & G), ethanol extract, lowering blood glucose levels

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: leaf matoa (Pometia pinnata JR Forst & G), ethanol extract, lowering blood glucose levels
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: magdalena kartika ningsih
Date Deposited: 20 Feb 2020 03:56
Last Modified: 20 Feb 2020 03:56
URI: http://repo.setiabudi.ac.id/id/eprint/2764

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