FORMULASI EKSTRAK BUAH JAMBU BIJI (Psidium guajava L.) SEBAGAI LOTION ANTIOKSIDAN

Bulan, Ayu Sri (2013) FORMULASI EKSTRAK BUAH JAMBU BIJI (Psidium guajava L.) SEBAGAI LOTION ANTIOKSIDAN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

White guava (Psidium guajava, L.) fruit extract has antioxidant activity, because it contains quercetin, a flavonoid compound. Utilization of guava fruit so far is limited for juice or eaten directly. This study was developed to make lotion preparations for maximum utilization as an antioxidant. Lotion is chosen because it is widely used for cosmetic preparations, and to find out whether the lotion from guava fruit extracts can be efficacious as an antioxidant. Thick extract of guava fruit was obtained by maceration method with ethanol 70% which then evaporated. The extract was made lotion preparation in 3 different series of concentrations. The three formulas were tested for its dispersive, adhesion, and viscosity. Determination of antioxidant activity in lotion was conducted by DPPH (1,1-diphenyl-2 pikrilhidrazil) using routine comparison, and the results were calculated by Inhibitory Concentration (IC50) value via probit analysis. The results of guava fruit extract lotion showed antioxidant activity. At day-2 IC50 value of formula I (18.5%) was 257.63 ppm, formula II (20.5%) 154.63 ppm, and formula III (22.5%) was 131.83 ppm. At week-4 the IC50 value of formula I (18.5%) was 274.45 ppm, formula II (20.5%) was 208.02 ppm, and formula III (22.5%) was 155.001 ppm. Formula with the highest antioxidant activity was formula III with concentration of 22.5% at the first week with IC50 value of 131.83 ppm. Keywords: Psidium guajava L., DPPH (1,1-diphenyl-2 pikrilhidrazil), lotion, antioxidant, Inhibitory Concentration (IC50)

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Psidium guajava L., DPPH (1,1-diphenyl-2 pikrilhidrazil), lotion, antioxidant, Inhibitory Concentration (IC50)
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	magdalena kartika ningsih
Date Deposited:	21 Feb 2020 03:41
Last Modified:	21 Feb 2020 03:41
URI:	http://repo.setiabudi.ac.id/id/eprint/2856

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