EFEK EKSTRAK ETANOL DAUN BELUNTAS (Pluchea indica Less) TERHADAP PENGHAMBATAN PENINGKATAN KADAR AST DAN ALT PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI PARASETAMOL

Ovikarian, Ovikarian (2014) EFEK EKSTRAK ETANOL DAUN BELUNTAS (Pluchea indica Less) TERHADAP PENGHAMBATAN PENINGKATAN KADAR AST DAN ALT PADA TIKUS PUTIH JANTAN GALUR WISTAR YANG DIINDUKSI PARASETAMOL. Skripsi thesis, Universitas Setia Budi Surakarta.

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01. INTISARI.pdf

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02. HALAMAN JUDUL - BAB I.pdf

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03. BAB II.pdf
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04. BAB III.pdf
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05. BAB IV.pdf
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06. BAB V - LAMPIRAN.pdf

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Abstract

Beluntas leaves medicinal plants that have a symbiotic content flavanoids, tannins, alkaloids, essential oils. This study is conducted to determine the effect of extracts ethanol of beluntas leave (Pluchea indica Less) on the inhibition of increase in AST and ALT as well as the correlation betwen the dose of extracts ethanol of beluntas leave with increase inhibitory effect of AST and ALT in male white rat induced with paracetamol. This research uses thirty rats divided into 6 groups. Groups I as a normal control group were fed and drinking. Groups II as a negative control given 1% CMC suspension. Groups III as positive control given suspension curliv plus® 21,6 mg/200 g BW. Groups IV, V, VI as a test solution behavior of ethanol extract of beluntas leaves 270 mg/200 g BW, 540 mg/200 g BW and 1080 mg/200 g BW. For 7 days and on the 7th day given suspension paracetamol 2,5 g/kg BW. All groups on days 0 and 8 were calculated inhibition increased AST and ALT . then the result were analyzed by paired T- test. The results showed that administration of extracts ethanol of beluntas leaves have any effect hepatoprotector because it can inhibit the increase of AST and ALT in male white rat after paracetamol induced as well as the correalation of beluntas leaves greater inhibitory effect of rising rates AST and ALT in male white rat after induced paracetamol. key words : beluntas leave, paracetamol, AST, ALT.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: beluntas leave, paracetamol, AST, ALT.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: B Supri Yadi
Date Deposited: 20 Nov 2019 04:54
Last Modified: 20 Nov 2019 04:54
URI: http://repo.setiabudi.ac.id/id/eprint/2916

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