UJI EFEKTIVITAS SUSU PROBIOTIK SAPI DAN KAMBING TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT YANG TERPAPAR FORMALIN

Rahaswari, Imelda (2013) UJI EFEKTIVITAS SUSU PROBIOTIK SAPI DAN KAMBING TERHADAP GAMBARAN HISTOPATOLOGI HATI MENCIT YANG TERPAPAR FORMALIN. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Milk with probiotics is contain with active cultures of lactic acid bacteria (LAB), which has many benefits for body like increase immune system and maintain gastrointestinal health. Formalin if we consumed cause poisoning and made liver’s cell damage. The study aims to determine effect of cow’s and goat’s milk with probiotic can reducing damage histological liver, which induce formalin, and knowing differences effects of some treatment. This study used 30 mices with six test groups: cow’s milk with probiotic (I), goat’s milk with probiotic (II), cow’s milk (III), goat's milk (IV), control normal group (V), and control formalin group (VI). Probiotic bacteria in milk is inoculated by three types LAB from starter yoghurt. This study was conducted 14 days, then made preparations liver histology and observed microscopically to cell necrosis like: piknotik, karioreksis, and kariolysis. Picture of the damage are hydropic degeneration and necrosis . Results of percent necrosis of liver cells: group I is 31,8%, group II is 24%, group III is 35.5%, Group IV is 27,5%, Group V is 0%, and group VI is 45,3% . The difference of percent necrosis between test groups showed a difference effect of cow’s and goat’s milk with probiotic in reducing damage histological of liver’s mice which induce formalin, and goat’ milk with probiotic more effective than else. The content of nutrients in milk such as proteins, fats, and vitamins, also added probiotic bacteria can minimize oxidative damage to the liver cells of mice wich induce formalin. Key words: milk with probiotik, formalin, liver histopatological

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	milk with probiotik, formalin, liver histopatological
Subjects:	Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica
Depositing User:	magdalena kartika ningsih
Date Deposited:	21 Feb 2020 03:45
Last Modified:	21 Feb 2020 03:45
URI:	http://repo.setiabudi.ac.id/id/eprint/2952

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