Christine, Melita Angelia (2013) PENGARUH FRAKSI AIR EKSTRAK ETANOLIK KULIT KAYU MANIS (Cinnamomum burmanii Bl.) DALAM SEDIAAN KRIM TERHADAP SIFAT FISIK KRIM DAN ANTIBAKTERI PADA Staphylococcus aureus. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
The cinnamon bark (Cinnamomum burmanii Bl.) contains of flavonoid, saponin, and tannin which acts as antibacterial. To facilitate the use of the extract then it made into cream, this is to prove that the extract of cinnamon bark can be made into cream and to prove the activity of cinnamon bark antibacterial against Staphylococcus aureus. The extraction method in this study is soxhletation with ethanol solvent 70% continued with acid hydrolysis with HCL 2M and being extracted three times using n-heksana, then the water fraction that resulted was evaporated until the remained weight and made into cream. The making of cream is made in three kind of formula with differences of concentration exctract are 1,57%, 2,57%, and 3,57%. Cream were tested by the physical characteristic test including organoleptic, homogenity, cream characteristic test, viskosity, dispersive power and adhesiveness. The tesing of antibacteria activity using diffusion method. The acquired data of the physical characteristic test being analized using two way ANOVA, and the acquired data of antibacteria activity being analized using one way ANOVA then continued by using t-test with a level of 95%. The results showed that the fraction of the water ethanolic extract of cinnamon bark affect the physical stability of cream cover the viscosity, and cohesiveness and adhesiveness. The water extract of cinnamon bark ethanolic cream’s has an antibacteria activity toward Staphylococcus aureus with Minimum Inhibition Concentration (MIC) 1,5 cm and the difference concentration of extract to the creams were affect toward the inhibition of each formula cream Key words : cinnamon, Staphylococcus aureus, cream, antibacterial
Item Type: | Thesis (Skripsi) |
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Uncontrolled Keywords: | cinnamon, Staphylococcus aureus, cream, antibacterial |
Subjects: | R Medicine > RS Pharmacy and materia medica |
Depositing User: | B Supri Yadi |
Date Deposited: | 20 Nov 2019 04:19 |
Last Modified: | 20 Nov 2019 04:19 |
URI: | http://repo.setiabudi.ac.id/id/eprint/2975 |
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