MASRUROH, SITI (2013) UJI AKTIVITAS ANTIJAMUR FRAKSI PETROLEUM ETER, FRAKSI ETIL ASETAT, DAN FRAKSI AIR DARI EKSTRAK ETANOLIK DAUN SIRIH MERAH (Piper crocatum Ruiz & Pav) TERHADAP Candida albicans ATCC® 10231. Skripsi thesis, Universitas Setia Budi Surakarta.
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Abstract
Red betel leaf (Piper crocatum) contains saponin, essential oil, flavonoid, alkaloid, tannin and polyphenol. The purpose of this study was to determine the activity of petroleum ether, ethyl acetate, and water fractions from ethanolic extract of red betel leaves (Piper crocatum) as antifungal against Candida albicans ATCC ® 10231. Red betel leaf was extracted by percolation using 96% ethanol, then fractionated using petroleum ether, ethyl acetate and water solvents. Petroleum ether, ethyl acetate, and water fractions from ethanolic extract of red betel leaves was tested its antifungal activity using dilution diffusion methods, with concentrations of 50%, 25%, 12.5%, 6.25%, 3.12%, 1, 56%, 0.78%, 0.39%, 0.195% and 0.098%. The results of this study showed that the Minimum Kill Concentration of water fraction was 0.195% and ethyl acetate fraction was 6.25% and petroleum ether fraction was 25%. Water fraction from ethanolic extract of red betel leaves had the most active antifungal activity than ethyl acetate and petroleum ether fractions. Keywords: Red betel leaves (Piper crocatum). Candida albicans ATCC ® 10231, diffusion and dilution methods.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | Red betel leaves (Piper crocatum). Candida albicans ATCC ® 10231, diffusion and dilution methods. |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | B Supri Yadi |
| Date Deposited: | 04 Dec 2019 07:39 |
| Last Modified: | 04 Dec 2019 07:39 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/3051 |
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