UJI AKTIVITAS ANTIBAKTERI EMULGEL MINYAK ATSIRI RIMPANG JAHE MERAH (Zingiber officinale var. rubrum) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA in vivo

Dewadita, Agung Geokistan (2019) UJI AKTIVITAS ANTIBAKTERI EMULGEL MINYAK ATSIRI RIMPANG JAHE MERAH (Zingiber officinale var. rubrum) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA in vivo. Skripsi thesis, Universitas Setia Budi.

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Abstract

Red ginger rhizome are known to have antibacterial activity against the bacterium Staplylococcus aureus. The rhizome of red ginger taken from the oil content is then formulated into emulgel preparations with variations in essential oil concentrates. The aim of this study was to determine the antibacterial activity of red ginger rhizome essential oil emulgel against the infection of Staplylococcus aureus ATCC 25923 in vivo. Red ginger rhizome of essential oil is taken by the steam distillation method for 5-6 hours. The oil of the red ginger rhizome is formulated into 3 formulas with a concentration difference of 15%, 20%, and 25%. The emulgel preparations of each formula were organoleptic, homogeneity, pH, viscosity, dispersion, adhesion and stability. Antibacterial test of emulgel preparations by observing the healing time of infection based on loss of erythema, pus, and decreasing the number of bacterial colonies carried out by the Plate count method. The data obtained were processed statistically by the Kolmogorov-Smirnov test followed by the two way ANOVA test. Red ginger essential oil can be made emulgel preparation with good physical quality and good stability at a concentration of 20% and 25%. The results of statistical tests on the antibacterial activity of red ginger rhizome essential oil emulgel revealed that the concentration of 25% had the most optimal healing effect on the bacterium Staphylococcus aureus ATCC 25923 which was infected in rabbits. Keyword : Zinggiber officinale var. rubrum , essential oil, emulgel, antibacterial, Staphylococcus aureus.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Zinggiber officinale var. rubrum , essential oil, emulgel, antibacterial, Staphylococcus aureus.
Subjects:	Q Science > QK Botany
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	15 Oct 2019 08:41
Last Modified:	15 Oct 2019 08:41
URI:	http://repo.setiabudi.ac.id/id/eprint/3397

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