STUDI INTERAKSI OBAT PADA PASIEN HIPERTENSI GERIATRI DI INSTALASI RAWAT INAP RSUD KARANGANYAR TAHUN 2018

Premasanti, Anak Agung (2019) STUDI INTERAKSI OBAT PADA PASIEN HIPERTENSI GERIATRI DI INSTALASI RAWAT INAP RSUD KARANGANYAR TAHUN 2018. Skripsi thesis, Universitas Setia Budi.

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Abstract

High prevalence of hypertension in Karanganyar causes serious health problems. Hypertension treatment in elderly patients cause drug use problems that can reduce effectiveness, increase side effects and drug interaction. The objective of this study was to identify drug interaction problems in elderly patients at Karanganyar Regional Public Hospital in 2018. A retrospective descriptive study was conducted in geriatric hypertensive patients with quota sampling method and cross-sectional study design. Samples of this study were all the geriatric hypertensive patients with or without comorbidities, age ≥ 60 years old, and prescribed more than 2 drugs at Inpatient Care Unit Karanganyar Hospital in 2018. Drug interactions were analyze with Lexicomp Reference-Drug Interaction Checker. The results showed that drug interactions were found in 104 patients (86.7%) with a total of 350 occurrences of drug interactions. Based on the severity of the cases, 25 cases (7.1%) were major interactions, 237 cases (67.7%) were moderate, and 88 cases (25.1%) were minor. The interaction based on the mechanism found 140 cases (40%) with the pharmacokinetic mechanism and 210 cases (60%) with the pharmacodynamic mechanism. Key word: Drug interaction, Geriatric, Hypertension, Karanganyar Regional Public Hospital

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Drug interaction, Geriatric, Hypertension, Karanganyar Regional Public Hospital
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 01 Nov 2019 03:42
Last Modified: 01 Nov 2019 03:42
URI: http://repo.setiabudi.ac.id/id/eprint/3497

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