Rosati, Dwi Indah (2019) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI n-HEKSAN, ETIL ASETAT, DAN AIR DARI RIMPANG BANGLE (Zingiber cassumunar Roxb.) TERHADAP BAKTERI MRSA (Methicillin Resistant Staphylococcus aureus) DENGAN METODE DIFUSI. Skripsi thesis, Universitas Setia Budi.
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Abstract
Bangle (Zingiber cassumunar Roxb.) contain triterpenoids, flavonoids, and tannins which have antibacterial activity. The purpose of the study was to determine the antibacterial activity of ethanol 96% extract, n-hexane fraction, ethyl acetate fraction, and water fraction from rimpang bangle to Methicillin Resistant Staphylococcus aureus bacteria based on the diameter of the inhibition zone. Rimpang bangle was extracted by maceration method using 96% ethanol solvent. Fractionation was carried out by liquid-liquid extraction using solvents of different levels of polarity, namely n-hexane, ethyl acetate, and water. The results of extraction and fractination were tested for antibacterial activity using diffusion method with a concentration of 50%, 10% 5%, and 1%. The positive control used was vancomycyn and negative control CMC Na 0,5%. The results of the antibacterial activity test were analyzed by two way ANOVA method. The results of the study of rhizome bangle showed extract, n-hexane fraction, and ethyl acetate fraction had antibacterial activity against Methicillin Resistant Staphylococcus aureus. The results of the diameter of the largest inhibition zone in the n-hexane fraction concentration of 50% is 12.06 mm. Twoway ANOVA analysis showed that the extract of 5% concentration were most effective in inhibiting Methicillin Resistant Staphylococcus aureus bacteria. Key word : antibacterial, fractions, Methicillin Resistant Staphylococcus aureus, rimpang bangle.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | antibacterial, fractions, Methicillin Resistant Staphylococcus aureus, rimpang bangle. |
| Subjects: | Q Science > QK Botany |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 01 Nov 2019 03:37 |
| Last Modified: | 01 Nov 2019 03:37 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/3629 |
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