Yulianti, Erika Dwi (2019) AKTIVITAS ANTIDEPRESAN MINYAK ATSIRI HERBA SELEDRI (Apium graveolens L.) PADA MENCIT PUTIH JANTAN DENGAN METODE ULTRASONIK MODIFIKASI. Skripsi thesis, Universitas Setia Budi.
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Abstract
Depression falls into the category of the most common diseases in the world. Treatment of depression can be done using the aroma of essential oils. One of the traditional plants that produce essential oils is celery herbs (Apium graveolens L.). This study aims to determine the antidepressant effect of celery herbs essential oils with various concentrations of 0.5%, 1%, 2%, and what is the most effective concentration, and the effect of increasing concentration on increasing motor activity and concentration. This study used 20 male white mice divided into five groups of ultrasonic sound-induced treatment with a frequency of 26,000 Hz to see motor activity (time of motor activity and number of displacements) and tested the labyrinth to determine the concentration (latency time) of mice before and after administration induction. The results showed that the aroma of celery herbs essential oil had a potential as an antidepressant seen from celery herbs essential oils 0.5% which was able to increase motor activity time. Which if seen based on the results of the percentage increase in the supply of celery herbs essential oils showed an increase in motor activity and only celery herbs essential oils were able to provide increased concentration, so celery herbs essential oils 0,5% is effective concentration. And the increase in the concentration of the celery herbs essential oils did not have an effect on increasing motor activity and concentration. Key word: essential oil, celery herbs, antidepressant, ultrasonic, labyrinth.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | essential oil, celery herbs, antidepressant, ultrasonic, labyrinth. |
| Subjects: | Q Science > QK Botany |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 01 Nov 2019 03:38 |
| Last Modified: | 01 Nov 2019 03:38 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/3640 |
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