FORMULASI DAN UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK KAYU SECANG (Caesalpinia sappan Linn) TERHADAP Staphylococcus aureus ATCC 25923 SEBAGAI ANTIBAKTERI

Rizki, Fahmi (2019) FORMULASI DAN UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK KAYU SECANG (Caesalpinia sappan Linn) TERHADAP Staphylococcus aureus ATCC 25923 SEBAGAI ANTIBAKTERI. Skripsi thesis, Universitas Setia Budi.

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Abstract

Staphylococcus aureus is a bacterial trigger for skin and penumunea. The plant that has been studied as an antibacterial is secang wood (Caesalpinia sappan L.). Hand sanitizer is a preparation designed to be applied to the hand to temporarily disable or inhibit the growth of microorganisme. The purpose of this study was to determine the combination of HPMC (Hydroxypropyl metylcellulose) and Carbopol which can provide good antibacterial effects and to evaluate the physical and chemical hand sanitizer preparations. Extract of secang wood using maceration method with 70% ethanol. The extract obtained was made by V formula for hand sanitizer preparation with variations in the concentration of hand sanitizer preparations. The preparation of hand sanitizer was tested for physical quality and stability. The antibacterial activity test for hand sanitizer was carried out in vitro by looking at the large inhibition zone. The data obtained is processed with statistical Analysis of Variance (ANOVA). The results of the activity test for the hand sanitizer extract of secang wood extract against Staphylococcus aureuis ATCC 25923 showed that all formulations had inhibitory diameters zone. The inhibited diameter zone of secang wood ethanol extract against Staphylococcus aureus ATCC 25923 is 17.26 mm; 18.42 mm; 19.77 mm; 21,19mm; 22.71 mm. The diameter zone of the inhibitory gel hand sanitizer of secang wood ethanol extract against Staphylococcus aureus ATCC 25923 is 12.88 mm; 13.72 mm; 14.98 mm; 17; 94 mm; 23.79 mm. Keywords: Secang wood, diffusion method, Staphylococcus aureus ATCC 25923, Hand sanitizer.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Secang wood, diffusion method, Staphylococcus aureus ATCC 25923, Hand sanitizer.
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	01 Nov 2019 03:39
Last Modified:	01 Nov 2019 03:39
URI:	http://repo.setiabudi.ac.id/id/eprint/3650

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