UJI EFEK ANALGETIK EKSTRAK BIJI LAMTORO (Leucaena leucocephala (Lamk.) de Wit) PADA MENCIT PUTIH JANTAN GALUR SWISS YANG DIINDUKSI ASAM ASETAT

Wibowo, Danang Saputro Maulana Yosi (2019) UJI EFEK ANALGETIK EKSTRAK BIJI LAMTORO (Leucaena leucocephala (Lamk.) de Wit) PADA MENCIT PUTIH JANTAN GALUR SWISS YANG DIINDUKSI ASAM ASETAT. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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Abstract

Treatment using traditional medicines is very popular nowadays. Lamtoro seeds are plants that contain flavonoids that have analgesic effect. The purpose of this study was to find out the analgesic effect of lamtoro seed in the white male mice induced acetate acid and to find the most effective dose. The study was conducted by laboratory experimental methods by testing the analgesic effects of lamtoro seed extracts on the white male mice swiss lines induced acetate acid. Test animals were divided into 5 groups, each group consisting of 5 mice. Group I (negative control) CMC, group II (positive control) acetosal at a dose of 1.2 mg / 20gBW, group III (lamtoro seed extract dose 14 mg / 20gBW), group IV (lamtoro seed extract dose 28 mg / 20gBW) and group V (lamtoro seed extract dose 56 mg / 20gBW). The amount of stretching is calculated every 10 minutes for 60 minutes. The data obtained were analyzed by ANOVA statistics and Tukey test. The results showed that lamtoro seed extract had an analgesic effect on male white mice. The dose of lamtoro seed extract which provides the most effective analgesic effect is a dose of 56 mg / 20gBW. Keywords : Lamtoro seed, induced acetate acid, analgesic

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: Lamtoro seed, induced acetate acid, analgesic
Subjects: R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 06 Nov 2019 07:40
Last Modified: 06 Nov 2019 07:40
URI: http://repo.setiabudi.ac.id/id/eprint/3731

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