UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL EKSTRAK ETANOL DAUN TREMBESI (Samanea saman (Jacq.) Merr) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA In Vivo PADA PUNGGUNG KELINCI

Stevani, Maria Wina (2019) UJI AKTIVITAS ANTIBAKTERI SEDIAAN GEL EKSTRAK ETANOL DAUN TREMBESI (Samanea saman (Jacq.) Merr) TERHADAP BAKTERI Staphylococcus aureus ATCC 25923 SECARA In Vivo PADA PUNGGUNG KELINCI. Skripsi thesis, Universitas Setia Budi.

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	Text COVER-BAB I.pdf Download (643kB)
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Abstract

Trembesi leaves contain bioactive compounds that are efficacious as antimicrobials. Active compounds that have antibacterial activity are flavonoids, alkaloids, saponins, phenols, and terpenoids. This study aims to determine the antibacterial activity of the ethanol extract of trembesi leaves (Samanea saman (Jacq.) Merr) against Staphylococcus aureus ATCC 25923 in vivo. Observation of rabbit healing can be seen from the length of time the loss of pus Extraction of trembesi leaves using maceration method with 96% ethanol. The extract was made into a gel preparation form based on HPMC (Hydroxypropyl methylcellulose). Gel is made into 5 formulas. Formula I as a negative control, formula II as a positive control given gentamicin, formula III with extract of 2 grams, formula IV with extract of 4 grams, and formula V with extract of 6 grams. Gel was tested for physical quality, stability, and antibacteria on Staphylococcus aureus ATCC 25923. The test results were analyzed statistically using the two-way ANOVA method. The results showed that 6% of the trembesi leaves ethanol extract gel had the best antibacterial activity of Staphylococcus aureus ATCC 25923. The results of the analysis of physical quality and stability of the gel fulfilling the treated conditions were statistically normally distributed and homogeneous. Keywords: Trembesi (Samanea saman (Jacq.) Merr), Gel, Staphylococcus aureus ATCC 25923

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Trembesi (Samanea saman (Jacq.) Merr), Gel, Staphylococcus aureus ATCC 25923
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	07 Nov 2019 07:25
Last Modified:	07 Nov 2019 07:25
URI:	http://repo.setiabudi.ac.id/id/eprint/3743

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