UJI AKTIVITAS ANTIBAKTERI SALEP EKSTRAK ETANOL BATANG PISANG AMBON (Musa acuminata Colla) PADA KELINCI YANG TERINFEKSI BAKTERI Staphylococcus aureus ATCC 25923

Aqila, Nisa (2019) UJI AKTIVITAS ANTIBAKTERI SALEP EKSTRAK ETANOL BATANG PISANG AMBON (Musa acuminata Colla) PADA KELINCI YANG TERINFEKSI BAKTERI Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

Ambon stem banana extract (Musa acuminata Colla) has an invitro proven antibacterial activity of Staphylococcus aureus. The active compounds contained are flavonoids, tannins and saponins. Ointment is a semipadat preparation that is practical and easy to use topically in healing wounds due to bacterial infections. The aim of the study was to determine the physical quality of ointment, the in vivo antibacterial activity of Staphylococcus aureus and the most optimal healing concentration on the ethanol extract of the Ambon banana stem (M.acuminata). Ethanol extract of Ambon banana stems was made by remaseration method with ethanol 96% solvent. Ointment is made in three extract concentrations of 15%, 30%, 45%. Ointment was tested for physical quality and data were analyzed by two-way ANOVA with a significance value of <0.05. Observation of recovery was seen in the length of time to recover from infection after administration of ointment, marked by pus loss and erythema. The most optimal healing concentration of the ointment formula was analyzed using oneway ANOVA. The results showed ointment of Ambon banana stems had good physical quality. Three ointment formulas have antibacterial activity of S.aureus ATCC 25923 with different healing times of 15, 13 and 7 days. The test results showed the most optimal concentration of 45% ointment in healing S.aureus ATCC 25923 bacterial infection. Keywords: Musa acuminata colla, antibacterial, Staphylococcus aureus ATCC 25923

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Musa acuminata colla, antibacterial, Staphylococcus aureus ATCC 25923
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	12 Nov 2019 07:35
Last Modified:	12 Nov 2019 07:35
URI:	http://repo.setiabudi.ac.id/id/eprint/3774

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