UJI EFEKTIVITAS EKSTRAK DAN SEDIAAN EKSTRAK KERING TEMULAWAK (Curcuma xanthorrhiza Roxb) SEBAGAI HEPATOPROTEKTOR PADA TIKUS JANTAN PUTIH GALUR WISTAR YANG DIINDUKSI PARASETAMOL

ZUHANA, Fanny Erl (2018) UJI EFEKTIVITAS EKSTRAK DAN SEDIAAN EKSTRAK KERING TEMULAWAK (Curcuma xanthorrhiza Roxb) SEBAGAI HEPATOPROTEKTOR PADA TIKUS JANTAN PUTIH GALUR WISTAR YANG DIINDUKSI PARASETAMOL. Skripsi thesis, Universitas Setia Budi Surakarta.

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Abstract

Temulawak is a medicinal plant that contains curcumin compounds that have antioxidant activity so potentially as a hepatoprotector. This study aims to compare the effectiveness of extract and dry extract of temulawak as a hepatoprotector. This study used 30 rats divided into 5 groups namely, control group I normal, negative control II, III positive control, IV given temulawak extract dose 800 mg / kgBB rat, V was given dry extract of ginger dose 800 mg / kgBB rat. Determination of initial SGOT and SGPT levels was performed on day 0. The administration of extracts and dried extracts was given on days 1-14. Day 11-13 was given paracetamol except the normal group. The final SGOT and SGPT assay was performed on day 14. The difference data of SGOT and SGPT was analyzed by ANOVA test and then used Tukey test to know the difference between the test group. The results showed that extract doses of 800 mg / kgBB and positive control (curcuma) there was no significant difference. The 800 mg / kgBB dose extract and positive control (curcuma) had comparable effectiveness, but the extract differed significantly with dry extract. Keywords: Temulawak (Curcuma xanthorrhiza Roxb.), Paracetamol, hepatoprotector.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Temulawak (Curcuma xanthorrhiza Roxb.), Paracetamol, hepatoprotector.
Subjects: R Medicine > RS Pharmacy and materia medica
Depositing User: Tifany Nur Arfiana
Date Deposited: 22 Feb 2019 09:44
Last Modified: 22 Feb 2019 09:44
URI: http://repo.setiabudi.ac.id/id/eprint/378

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