UJI AKTIVITAS ANALGESIK EKSTRAK DAUN BIDARA (Ziziphus mauritiana Lamk.) TERHADAP MENCIT PUTIH JANTAN (Mus musculus) DENGAN METODE WRITHING TEST

Agustina, Revia (2019) UJI AKTIVITAS ANALGESIK EKSTRAK DAUN BIDARA (Ziziphus mauritiana Lamk.) TERHADAP MENCIT PUTIH JANTAN (Mus musculus) DENGAN METODE WRITHING TEST. Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

[img] Text
BAB II.pdf
Download (369kB)
[img] Text
BAB III.pdf
Download (223kB)
[img] Text
BAB IV.pdf
Download (234kB)
[img] Text
BAB V-LAMPIRAN.pdf
Download (1MB)
[img] Text
COVER-BAB I.pdf
Download (477kB)
[img] Text
INTISARI.pdf
Download (91kB)
[img] Text
PERNYATAAN PUBLIKASI.pdf
Download (351kB)

Abstract

Pain is an unpleasant sensory experience related to tissue damage, both actual and potential, or described in the form of damage. Bidara leaves have the potential as an analgesik. This study aims to determine the analgesic effect of bidara leaf extract and determine teh dose of analgesic effect of bidara leaf extract and determine the effective dose of bidara leaf extract by method whithing test. This research was carried out by maceration method with 70% ethanol. 25 male white mice were divided into 5 groups, namely aquadest negative control, positive control of ibuprofen, bidara leaf extract 100mg/Kg BB, 150mg/Kg BB, 200mg/Kg BB, then seen stretching response, ie both pairs of legs forward and backward and abdomen pressed until the floor appers maximum after 5 minutes of induction. The data of stretching mice obtained were the analyzed by ANOVA test, then used TUKEY HSD to determine the differences between the test groups. The results showed extracts of 100mg/Kg BB, 150mg/Kg BB, 200mg/Kg BB, and positive controls has an effect as an analgesic. 150mg/Kg BB extract dose comparable to positive control, that the dose has optimal analgesic activity. compounds flavonoids contained in bidara leaves are thought to have analgesic effects. Key words : analgesic, tail flick, writhing test, bidara leaves

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: analgesic, tail flick, writhing test, bidara leaves
Subjects: Q Science > QK Botany
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 16 Nov 2019 02:25
Last Modified: 16 Nov 2019 02:25
URI: http://repo.setiabudi.ac.id/id/eprint/3801

Actions (login required)

View Item View Item
Repository USB is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.