EFEK PENURUNAN KADAR KOLESTEROL TOTAL DAN TRIGLISERIDA EKSTRAK ETANOL 96% KUNYIT PUTIH (Curcuma zedoaria Rosc.) TERHADAP MENCIT PUTIH JANTAN YANG DIINDUKSI PROPILTIOURASIL (PTU)

Eriyatnaning, Vinna Pramadika (2019) EFEK PENURUNAN KADAR KOLESTEROL TOTAL DAN TRIGLISERIDA EKSTRAK ETANOL 96% KUNYIT PUTIH (Curcuma zedoaria Rosc.) TERHADAP MENCIT PUTIH JANTAN YANG DIINDUKSI PROPILTIOURASIL (PTU). Karya Tulis Ilmiah thesis, Universitas Setia Budi Surakarta.

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1. INTISARI DAN ABSTRAK.pdf
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2. FORM PUBLIKASI.pdf
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3. COVER - BAB I.pdf
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Abstract

White turmeric rhizome contains various chemical components including tannin, curcumin, starch, sugar, essential oils, resin, saponins, and flavonoids compounds that have hypolipidemic activity against total cholesterol levels and reduce triglyceride levels by increasing lipoprotein lipase. This study aims to determine whether ethanol extract of white turmeric rhizome Can improve lipid profile and find out effective doses that can improve lipid profiles in white male mice induced by PTU. A pretest-postest control group design study applied male white mice induced by propylthiouracil (PTU). Thirty male white mice were divided into six groups. Group I was normal control, group II was given 0.5% Na-CMC, group III was given simvastatin drug, group IV, V and VI were given ethanol extract with different dose variants. Measurement of total cholesterol levels using the Multicheck strip test method and on the exchange of tiglyceride levels using the GPO-PAP method. The data obtained were analyzed using Kolmogorof-Smornov statistical test, One Way ANOVA test and Post Hoc Test, namely Tukey. White turmeric ethanol extract has been shown to improve lipid profile in male white mice induced by PTU.The dose of extract which can reduce which can reduce total cholesterol and tryglicerida levels is a dose of 5,6 mg/20g BB mice, 11,2 mg/10g BB mice and 16,8 mg/20g BB mice. The effective dose of ethanol extract of white turmeric rhizome that can improve lipid profile in male white mice induced by PTU is a dose and 16.8 mg /20 gram BB mice. Keywords : White Turmeric Rhizome (Curcuma zedoaria Rosc.), Total Cholesterol, Total Triglyceride, PTU.

Item Type: Thesis (Karya Tulis Ilmiah)
Uncontrolled Keywords: White Turmeric Rhizome (Curcuma zedoaria Rosc.), Total Cholesterol, Total Triglyceride, PTU
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: Fakultas Farmasi > Prodi D3 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 16 Nov 2019 02:05
Last Modified: 16 Nov 2019 02:05
URI: http://repo.setiabudi.ac.id/id/eprint/3812

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