UJI AKTIVITAS TROMBOLITIK EKSTRAK ETANOL AKAR ALANG-ALANG (Imperata cylindrica (L.)) TERHADAP PERSENTASE LISIS BEKUAN DARAH DAN PENURUNAN JUMLAH TROMBOSIT SECARA EX VIVO

Triharyanti, Nurul (2019) UJI AKTIVITAS TROMBOLITIK EKSTRAK ETANOL AKAR ALANG-ALANG (Imperata cylindrica (L.)) TERHADAP PERSENTASE LISIS BEKUAN DARAH DAN PENURUNAN JUMLAH TROMBOSIT SECARA EX VIVO. Skripsi thesis, Universitas Setia Budi.

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Abstract

Alang-alang (Imperata cylindrical L) root has known to have a thrombolytic effect. Thrombolytic is a mechanism to break down blood clots. This study aimed to determine thrombolytic activity and optimal concentration of alang-alang root extract. Percentage of clot lysis and reduction of blood platelet count were used as parameters in this study. This study used six male rats which were divided into five groups as follow: negative control and ethanolic extract of the alang-alang root at concentration 2,5 mg/ml, 5 mg/ml, 10 mg/ml and 20 mg/ml. The data were tested for normality by using Kolmogorov-Smirnov. After the data were found not homogen and not normally distributed, the data were test by using Kruskall- Wallis. The results showed that alang-alang root ethanolic extract could lyse blood clots and reduced blood platelet count in male rats. Concentration of alang-alang root ethanolic extract that had thrombolytic activity were 2,5 ; 5 ; 10 ; 20 mg/ml. Keywords : Activity trombolitic, root ethanolic extract of alang-alang, lysis of blood clots and reduce platelet count.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Activity trombolitic, root ethanolic extract of alang-alang, lysis of blood clots and reduce platelet count.
Subjects: R Medicine > R Medicine (General)
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 16 Nov 2019 02:06
Last Modified: 16 Nov 2019 02:06
URI: http://repo.setiabudi.ac.id/id/eprint/3817

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