UJI AKTIVITAS ANTI-AGING KRIM EKSTRAK ETANOL DAUN KERSEN PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UVA

Permatasari, Paula Intan (2019) UJI AKTIVITAS ANTI-AGING KRIM EKSTRAK ETANOL DAUN KERSEN PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UVA. Skripsi thesis, Universitas Setia Budi.

	Text INTISARI ABSTRAK.pdf Download (14kB)
	Text PERNYATAAN PUBLIKASI.pdf Download (240kB)
	Text COVER - BAB I.pdf Download (1MB)
	Text BAB II.pdf Download (317kB)
	Text BAB III.pdf Download (341kB)
	Text BAB IV.pdf Download (690kB)
	Text BAB V - LAMPIRAN.pdf Download (3MB)

Abstract

Free radicals can cause premature aging. The effects of UVA rays that are a source of free radicals can be prevented with antioxidant compounds. Antioxidants are compounds that can counteract or reduce the negative effects of oxidants in the body. Cream preparations of kersen ethanol extract (Muntingia calibura L) have antioxidant effectiveness. This research was conducted to determine the cream activity of kersen ethanol extract as anti-aging in vivo using rabbits exposed to UVA rays. Kersen leaf extract (Muntingia calabura L) is carried out by determining the moisture content and identifying the chemical content. The cream preparations were made and then tested for physical quality. The anti-aging test uses 5 rabbits. The rabbit's back is shaved, UVA induction is done 6 hours a day for 2 weeks. Rabbit back skin smeared with kersen leaf extract cream 3%, 6%, and 9% for 30 days. Observation of the parameters of percent collagen, percent elasticity, and percent moisture were carried out before induction, after induction, and after the rabbit's back was smeared with cream. The results of physical quality tests for cream F1, F2, F3, and F4 meet the organoleptic requirements, pH, homogeneity, viscosity, and dispersion. The stability test results for F1, F2, F3 and F4 creams meet the organoleptic and pH requirements. The primary irritation test results show that the cream is very little irritating to the skin and the results of the ocular irritation test are not irritating. The results showed that the cream of kersen leaf extract with a concentration of 3% gave the most effective anti-aging effect. Keywords: kersen leaf extract, anti-aging activity, cream, safety test, Skin Analyzer

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	kersen leaf extract, anti-aging activity, cream, safety test, Skin Analyzer
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	15 Nov 2019 07:02
Last Modified:	15 Nov 2019 07:02
URI:	http://repo.setiabudi.ac.id/id/eprint/3821

Actions (login required)

View Item