UJI AKTIVITAS ANTIOKSIDAN KOMBINASI FRAKSI n-BUTANOL DAUN SIRSAK (Annona muricata L.) DAN FRAKSI ETIL ASETAT DAUN ALPUKAT (Persea americana Mill) TERHADAP RADIKAL DPPH

Eliyana, Rika (2019) UJI AKTIVITAS ANTIOKSIDAN KOMBINASI FRAKSI n-BUTANOL DAUN SIRSAK (Annona muricata L.) DAN FRAKSI ETIL ASETAT DAUN ALPUKAT (Persea americana Mill) TERHADAP RADIKAL DPPH. Skripsi thesis, Universitas Setia Budi.

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Abstract

Soursop plants (Annona muricata L.) and Avocado Plants (Persea americana Mill) are plants that have benefits as traditional medicine. Soursop leaves (Annona muricata L.) and avocado leaves (Persea americana Mill) are plants that contain compounds of flavonoids, saponins, tannins, and polyphenols which have antioxidant activity. The purpose of this study was to determine the antioxidant activity of a combination of n-butanol fraction of soursop leaves and ethyl acetate fraction of avocado leaves against DPPH radicals (1,1-Diphenyl-2-Pycrylhidrazil) which made three comparisons, namely 1: 1, 1: 2, and 2: 1. Extraction was carried out by maceration using methanol solvent, then the methanol extract of soursop leaves was fractionated using n-hexane, ethyl acetate, nbutanol and water solvents. The methanol extract of avocado leaves was fractionated using n-hexane, ethyl acetate, and water solvents. Testing of antioxidant activity using the DPPH (1,1-Diphenyl-2-Pycrylhidrazil) method by spectrophotometry. The results showed that the combination of n-butanol fraction of soursop leaves and the ethyl acetate fraction of avocado leaves had antioxidant activity. The IC50 ratio of 1:1 is 8.15 ppm, the ratio of 1:2 is 7.28 ppm, and the ratio of 2:1 is 6.98 ppm. Ratio of 2:1 is the strongest combination. Keyword : soursop leaf, avocado leaf, antioxidant, DPPH, IC50.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: soursop leaf, avocado leaf, antioxidant, DPPH, IC50.
Subjects: Q Science > QK Botany
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Tifany Nur Arfiana
Date Deposited: 14 Nov 2019 04:45
Last Modified: 14 Nov 2019 04:45
URI: http://repo.setiabudi.ac.id/id/eprint/3846

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