Safitri, Rina (2019) FORMULASI EMULGEL EKSTRAK ETANOL DAUN PEPAYA (Carica papaya L.) SEBAGAI PENYEMBUH LUKA BAKAR DERAJAT II SUPERFISIAL PADA PUNGGUNG KELINCI New Zealand. Skripsi thesis, Universitas Setia Budi.
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Abstract
Second degree burns are damage that occurs in the epidermis and part of the dermis. Papaya leaf (Carica papaya L.) can be used as an alternative burner because it contains compounds such as flavonoids, saponins, and tannins. Emulgel is a preparation intended for topical use. This study aims to determine the ethanol extract of papaya leaves can be formulated into a good emulgel, as well as knowing the activity of papaya leaves as a healer of deformed burns II and knowing the effective concentration of papaya leaves ethanol extract emulgel as a burn wound healer. The test used 5 rabbits as test animals and 5 wound sites were made on the rabbit's back. Making wounds using heated metal plates. At 5 wound sites smeared with papaya leaves ethanol extract emulgel with a concentration of 5%, 10%, 15%, negative control, and positive control for 14 days. Emulgel physical properties were tested by organoleptic, pH, viscosity, adhesion, dispersion, and freeze and thaw test. The results of measurements of wound diameter were statistically analyzed using two way anova. The results showed that all concentrations of the papaya leaf ethanol extract emulgel formula had an effect as a burn wound healer. The 5% emulgel concentration formula showed the best effect in healing burns with an average percentage of healing burns which was almost equivalent to positive control of 99.407%. Keywords: burns, papaya leaves (Carica papaya L.), Rabbit, Emulgel
| Item Type: | Thesis (Skripsi) |
|---|---|
| Uncontrolled Keywords: | burns, papaya leaves (Carica papaya L.), Rabbit, Emulgel |
| Subjects: | R Medicine > RS Pharmacy and materia medica |
| Divisions: | Fakultas Farmasi > Prodi S1 Farmasi |
| Depositing User: | Tifany Nur Arfiana |
| Date Deposited: | 14 Nov 2019 04:44 |
| Last Modified: | 14 Nov 2019 04:44 |
| URI: | http://repo.setiabudi.ac.id/id/eprint/3849 |
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