UJI AKTIVITAS SITOTOKSIK EKSTRAK ETANOL TANAMAN KELADI TIKUS (Typhonium flagelliforme) TERHADAP SEL KANKER HATI HepG2

Nugraheni, Wahyu (2019) UJI AKTIVITAS SITOTOKSIK EKSTRAK ETANOL TANAMAN KELADI TIKUS (Typhonium flagelliforme) TERHADAP SEL KANKER HATI HepG2. Skripsi thesis, Universitas Setia Budi Surakarta.

[img] Text
BAB II.pdf
Download (465kB)
[img] Text
BAB III.pdf
Download (497kB)
[img] Text
BAB IV.pdf
Download (680kB)
[img] Text
BAB V-LAMPIRAN.pdf
Download (846kB)
[img] Text
COVER- BAB I.pdf
Download (784kB)
[img] Text
INTISARI.pdf
Download (294kB)
[img] Text
LEMBAR PERSETUJUAN.pdf
Download (417kB)

Abstract

Based on estimation of Globacan (2012) liver cancer is the fourth leading cause of death that often occurs in men rather than women. In Indonesia there are many herbs that potentially as anticancer, one wich keladi tikus herba. Cytotoxic activities on hepar cancer cells HepG2 have been found in the ethanolic extract of keladi tikus herba. The purpose of this research is to know the of ethanolic extract of keladi tikus herba on hepar cancer HepG2. This type of research was laboratory experimental. The keladi tikus herba was extracted by maceration method using 96 % ethanol solvent. The cytotoxic test of ethanolic extract with Doxorubicin against hepar cancer cell HepG2 was done by MTT assay methode with a concentration series of 1000; 500; 250; 125; 62.5; 31.2; 15.6 μg / ml while in the positive control using the concentration series namely 2; 1; 0.5; 0.25; 0.125; 0.0625; 0.03125 μg / ml. Data analysis was performed using linier regrestion between live cell percentage and log concentration to obtain IC50 value. The results showed that ethanolic extract of keladi tikus herba had cytotoxic effect shown by IC50 value of 136,7 μg/ml. Keywords: Ethanolic Extract Kelaadi Tikus Herba, Doxorubicin, Cytotoxic, Cell HePG2.

Item Type: Thesis (Skripsi)
Uncontrolled Keywords: Ethanolic Extract Kelaadi Tikus Herba, Doxorubicin, Cytotoxic, Cell HePG2
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Farmasi > Prodi S1 Farmasi
Depositing User: Mrs NOVI HANDAYANI
Date Deposited: 16 Nov 2019 03:02
Last Modified: 16 Nov 2019 03:02
URI: http://repo.setiabudi.ac.id/id/eprint/3905

Actions (login required)

View Item View Item
Repository USB is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.