UJI AKTIVITAS ANTI AGING KRIM EKSTRAK ETANOL DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A

Apriliani, Melisa (2020) UJI AKTIVITAS ANTI AGING KRIM EKSTRAK ETANOL DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA KULIT PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A. Skripsi thesis, Universitas Setia Budi.

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Abstract

Exposure to UV light, pollution and unhealthy lifestyles trigger the formation of free radicals that can accelerate the aging process on the skin. Flavonoid compounds in purple sweet potato leaves have antioxidant properties that can neutralize free radicals so that they can improve the signs of aging on the skin. This study aims to determine the manufacture of cream with good physical quality and stability, determine the activity of purple sweet potato leaf extract cream as antiaging in vivo using New Zealand rabbits exposed to UV-A rays, as well as safety tests with primary and ocular irritation parameters. Purple sweet potato leaf extract was made using maceration method, then the extract was carried out to identify the chemical content. The extract is made as a cream preparation and tested for physical quality. Antiaging activity testing using a skin analyzer against 5 rabbits. Shaved rabbit hair, induction of UV-A rays is carried out 6 hours a day for 2 weeks. Rabbit's back skin is applied with cream of purple sweet potato leaf extract for 28 days. The parameters of percent collagen, percent elasticity, percent humidity, and pore area were observed before induction, after induction and after the rabbit's back was applied with cream. The results showed that all formulas met the physical quality and stability requirements. The results of 10% purple sweet potato leaf cream extract are the most effective antiaging effect with parameters of percent collagen, percent elasticity, percent humidity and pore area. Primary irritation test results show the cream is slightly irritating. Ocular irritation test results show the cream does not irritate. key words: purple sweet potato leaf extract, antiaging activity, cream, skin analyzer

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	purple sweet potato leaf extract, antiaging activity, cream, skin analyzer
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	29 Mar 2022 07:55
Last Modified:	29 Mar 2022 07:55
URI:	http://repo.setiabudi.ac.id/id/eprint/4663

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