UJI AKTIVITAS ANTI AGING KRIM MINYAK BIJI NYAMPLUNG (Calophyllum inophyllum L. ) PADA PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A

Wiratantri, Fitra Indah (2020) UJI AKTIVITAS ANTI AGING KRIM MINYAK BIJI NYAMPLUNG (Calophyllum inophyllum L. ) PADA PUNGGUNG KELINCI NEW ZEALAND YANG DIPAPAR SINAR UV-A. Skripsi thesis, Universitas Setia Budi.

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Abstract

UV-A rays produce free radicals that play a role in skin aging. Free radicals can be prevented by the presence of antioxidants. Antioxidants can reduce the negative effects of free radicals in the body. Nyamplung seed oil (Calophyllum inophyllum L.) have antioxidant activity. This study aims to determine the activity of nyamplung seed oil (Calophyllum inophyllum L.) as an anti aging in vivo using rabbits exposed to UV-A rays Nyamplung seed oil (Calophyllum inophyllum L.) was characterized by refractive index and specific gravity then chemical content was identified. The oil is made as a cream preparation and then tested for its physical quality. Anti aging activity testing was carried out on the backs of 5 rabbits that had been exposed to UV-A rays for 6 hours in 2 weeks. The skin of the rabbit's back is smeared with nyamplung seed oil cream preparations 10; 15 and 20%. Observation parameters include percent collagen, percent elasticity, percent moisture and pore area, carried out before induction, after induction and application of cream for 4 weeks using a Skin Analyzer The physical quality test results of F1, F2, F3 and F4 meet organoleptic, homogeneity, pH, viscosity, and dispersal requirements. The results of the F1, F2, F3 and F4 stability tests meet the pH and viscosity requirements. Primary irritation test results showed the cream was slightly irritating. Ocular irritation test results show the cream does not irritate. The results showed nyamplung seed oil cream with a concentration of 15% gave the most effective anti-aging effect. Keywords: nyamplung seed oil, anti aging activity, cream, safety test, Skin Analyzer

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	nyamplung seed oil, anti aging activity, cream, safety test, Skin Analyzer
Subjects:	R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	09 Jun 2022 03:28
Last Modified:	09 Jun 2022 03:28
URI:	http://repo.setiabudi.ac.id/id/eprint/4763

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