PENGARUH PEMBERIAN EKSTRAK ETANOL BUNCIS (Phaseolus vulgaris L.) TERHADAP PENINGKATAN DAYA INGAT PADA TIKUS PUTIH JANTAN DENGAN METODE MORRIS WATER MAZE

Nathalina, Destria (2020) PENGARUH PEMBERIAN EKSTRAK ETANOL BUNCIS (Phaseolus vulgaris L.) TERHADAP PENINGKATAN DAYA INGAT PADA TIKUS PUTIH JANTAN DENGAN METODE MORRIS WATER MAZE. Skripsi thesis, Universitas Setia Budi.

	Text INTISARI.pdf Download (91kB)
	Text LEMBAR PERNYATAAN PERSETUJUAN PUBLIKASI KARYA ILMIAH UNTUK KEPENTINGAN AKADEMIS.pdf Download (998kB)
	Text COVER-BAB I.pdf Download (231kB)
	Text BAB II.pdf Restricted to Repository staff only Download (421kB) | Request a copy
	Text BAB III.pdf Restricted to Repository staff only Download (227kB) | Request a copy
	Text BAB IV.pdf Restricted to Repository staff only Download (769kB) | Request a copy
	Text BAB V-LAMPIRAN.pdf Download (2MB)

Abstract

Memory is ability to remember and store information. Symptoms of memory loss are dementia to the worst conditions causing Alzheimer's. This decrease because the amount of the neurotransmitter acetylcholine is unstable and damage to the pyramidal cells in the hippocampus area by several factors. Beans are thought to have activity in improving memory. The purpose of this study was to determine the effect of giving ethanol extracts of beans (EEB), determine the effective dose of EEB, and determine the histopathological of the hippocampus in the rat brain. Beans are made into a powder and extracted by maceration method using 70% ethanol. Tests were carried out on 25 rats divided into 5 treatment groups are positive (Ginkgo biloba), negative (Na-CMC 1%), EEB dose 100; 200; and 400 mg/kgBW. Test uses Morris Water Maze method and latency time data is analyzed using Anova one-way (p<0.05) and histopathological on rat brain organs analyzed by qualitative method. Identification of compounds from bean powder and EEB containing flavonoids, alkaloids, phenolics, tannins, steroids, triterpenoids, and saponins. The results showed EEB dose of 100; 200; and 400 mg/KgBW has the activity to improve memory. Dose of 400 mg/KgBW shows effective enhancement activity and histopathological of the hippocampus show a good number of pyramidal cells approaching Ginkgo biloba. Keywords: Memory; Ethanol Extract of Beans; Morris Water Maze; Histopathology.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Memory; Ethanol Extract of Beans; Morris Water Maze; Histopathology.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	09 Jun 2022 03:28
Last Modified:	09 Jun 2022 03:28
URI:	http://repo.setiabudi.ac.id/id/eprint/4782

Actions (login required)

View Item