UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK KULIT NANAS (Ananas comosus (L.) Merr) TERHADAP Staphylococcus aureus ATCC 25923

Putri, Bahana Eliza (2020) UJI AKTIVITAS GEL HAND SANITIZER EKSTRAK KULIT NANAS (Ananas comosus (L.) Merr) TERHADAP Staphylococcus aureus ATCC 25923. Skripsi thesis, Universitas Setia Budi.

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Abstract

Pineapple skin (Ananas comosus (L.) Merr) is known to have antibacterial activity against Staphylococcus aureus bacteria. The active compounds in pineapple peel that have antibacterial activity are flavonoids, alkaloids, tannins, and saponins.The purpose of this study was to formulate a hand sanitizer gel from ethanol extract of pineapple peel which has good physical quality and stability and has activity against Staphylococcus aureus bacteria. Pineapple peel was extracted by maceration method for 5 days with 70% ethanol solvent. The ethanol extract of pineapple peel is formulated into 3 formulas with differences in the concentration of ethanol extract of 3%, 6%, and 9%. The gel preparations of each formula were tested for organoleptic, homogeneity, pH, viscosity, dispersibility, adhesion, stability and activity against Staphylococcus aureus bacteria. Physical quality test data and activity against Staphylococcus aureus were analyzed statistically by the Shapirow-Wilk test followed by one way ANOVA test. The results showed that the hand sanitizer gel preparation of ethanol extract of pineapple peel with various concentrations had good physical quality and stability. The hand sanitizer gel of pineapple peel ethanol extract with various concentrations has antibacterial activity. The results of the antibacterial activity test showed that the hand sanitizer gel preparation of pineapple peel extract against Staphylococcus aureus with a concentration of 9% gave the most active antibacterial effect. Keywords: Ananas comosus L. Merr, antibacterial, gel hand sanitizer, Staphlococcus aureus.

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Ananas comosus L. Merr, antibacterial, gel hand sanitizer, Staphlococcus aureus.
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	09 Jun 2022 03:30
Last Modified:	09 Jun 2022 03:30
URI:	http://repo.setiabudi.ac.id/id/eprint/4811

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