KAJIAN PUSTAKA AKTIVITAS SITOTOKSIK Garcinia sp.TERHADAP BERBAGAI KULTUR SEL KANKER RAHIM DAN PENGARUHNYA TERHADAP EKSPRESI GEN BERBAGAI PROTEIN

Arianto, Elsye Adelina (2020) KAJIAN PUSTAKA AKTIVITAS SITOTOKSIK Garcinia sp.TERHADAP BERBAGAI KULTUR SEL KANKER RAHIM DAN PENGARUHNYA TERHADAP EKSPRESI GEN BERBAGAI PROTEIN. Skripsi thesis, Universitas Setia Budi.

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Abstract

Cervical cancer is abnormal cell that grow in part of female reproductive system, also called the neck of the uterus, the cervix connect the uterus to the vagina. This research purpose is to investigate the cytotoxic activity of Garcinia sp. on the study of various cervical cancer cells cultures and its effect on gene expression of various of various protein. This research started with extraction of mangosteen leaf with maseration method. Mangosteen leaves were tested by tube method and TLC method to know the component in it. of The study of cytotoxic activity was carried out using review jornal to know the cytotoxic activity of Garcinia sp. on various cervical cancer cells culture and its effect on gene expression of various protein. The result of of this study was extract of mangosteen leaves contains pholiphenols, flavonoids, tannins, saponins, and triterpenoids compounds. Journal review of cytotoxic activity showed that Garcinia sp. had cytotoxic activity on various cancer cells (HeLa cells, SiHa cells, HCE-1 cells) and effect to increase or depress gene expression of various protein (Bcl2, Caspase, Sitochrome-C, Bax, TR3, hnRNPK). Keywords: Cytotoxic, Garcinia sp, cell HeLa, cell SiHa,

Item Type:	Thesis (Skripsi)
Uncontrolled Keywords:	Cytotoxic, Garcinia sp, cell HeLa, cell SiHa,
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Fakultas Farmasi > Prodi S1 Farmasi
Depositing User:	Tifany Nur Arfiana
Date Deposited:	09 Jun 2022 03:30
Last Modified:	09 Jun 2022 03:30
URI:	http://repo.setiabudi.ac.id/id/eprint/4822

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